C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000787 Ddx3x 10090 + X:13280970-13294052 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000804 Ddx3x-001 13280970-13294052 protein_coding
  ENSMUST00000123096 Ddx3x-004 13287284-13288852 retained_intron
  ENSMUST00000149639 Ddx3x-005 13287785-13289915 retained_intron
  ENSMUST00000153611 Ddx3x-003 13281032-13287872 retained_intron
  ENSMUST00000153851 Ddx3x-002 13281022-13292022 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000804ENSMUST00000149639ENSMUST00000153611ENSMUST00000153851
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000804 25.262±7.71 16.784±2.67 34.555±5.36 36.376±8.56 17.875±1.18 17.658±2.66 17.577±4.13 26.291±3.77 28.385±8.71 29.003±3.93 30.645±2.15 36.231±33.02 70.881±16.93 3.601±0.36
ENSMUST00000149639 N/A N/A N/A 59.531±0.00 N/A N/A N/A N/A N/A N/A N/A 137.656±0.00 125.170±40.10 9.987±0.00
ENSMUST00000153611 N/A N/A N/A 62.297±0.00 N/A N/A N/A N/A N/A N/A N/A 180.822±0.00 131.902±62.83 49.384±0.00
ENSMUST00000153851 N/A N/A N/A N/A N/A 13.285±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005QB CIL_0005QB_0002 CGP X:13071498-13294052
CIL_0007LW CIL_0007LW_0002 UCNEbase X:13169486-13522078
CIL_0001X4 CIL_0001X4_0003 CGP X:13280970-13489313

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 ISS DNA binding
GO:0003723 ISS RNA binding
GO:0004003 ISS ATP-dependent DNA helicase activity
GO:0004004 ISS ATP-dependent RNA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005741 IEA mitochondrial outer membrane
GO:0005852 ISS eukaryotic translation initiation factor 3 complex
GO:0006200 IEA ATP catabolic process
GO:0006351 IEA transcription, DNA-templated
GO:0007059 ISS chromosome segregation
GO:0008134 ISS transcription factor binding
GO:0008143 ISS poly(A) binding
GO:0008190 ISS eukaryotic initiation factor 4E binding
GO:0008625 ISS extrinsic apoptotic signaling pathway via death domain receptors
GO:0009615 ISS response to virus
GO:0010494 ISS cytoplasmic stress granule
GO:0010501 ISS RNA secondary structure unwinding
GO:0016887 ISS ATPase activity
GO:0017148 ISS negative regulation of translation
GO:0022627 ISS cytosolic small ribosomal subunit
GO:0030307 ISS positive regulation of cell growth
GO:0031333 ISS negative regulation of protein complex assembly
GO:0031369 ISS translation initiation factor binding
GO:0032508 ISS DNA duplex unwinding
GO:0034063 ISS stress granule assembly
GO:0035556 ISS intracellular signal transduction
GO:0035613 ISS RNA stem-loop binding
GO:0042256 ISS mature ribosome assembly
GO:0043024 ISS ribosomal small subunit binding
GO:0043065 ISS positive regulation of apoptotic process
GO:0043066 ISS negative regulation of apoptotic process
GO:0043154 ISS negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043280 ISS positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045087 ISS innate immune response
GO:0045727 ISS positive regulation of translation
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0045948 ISS positive regulation of translational initiation
GO:0048027 ISS mRNA 5'-UTR binding
GO:0071243 ISS cellular response to arsenic-containing substance
GO:0071470 ISS cellular response to osmotic stress
GO:0097193 ISS intrinsic apoptotic signaling pathway
GO:1900087 ISS positive regulation of G1/S transition of mitotic cell cycle
GO:2001243 ISS negative regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005774 pl10 pl10 protein_coding Danio_rerio
ENSDARG00000020573 ddx3 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 protein_coding Danio_rerio
ENSG00000215301 DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked protein_coding Homo_sapiens

Loading