C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: spectrin repeat containing, nuclear envelope 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000063450 Syne2 10090 + 12:75818134-76110926 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000044217 Syne2-201 75818318-76110900 protein_coding
  ENSMUST00000085280 Syne2-006 76031614-76110920 protein_coding
  ENSMUST00000124685 Syne2-005 75909218-75913887 retained_intron
  ENSMUST00000126903 Syne2-013 76081939-76097981 nonsense_mediated_decay
  ENSMUST00000131480 Syne2-014 76072016-76094436 protein_coding
  ENSMUST00000132161 Syne2-008 76087760-76110926 nonsense_mediated_decay
  ENSMUST00000133623 Syne2-002 75818323-75891049 retained_intron
  ENSMUST00000139204 Syne2-007 76048578-76110900 protein_coding
  ENSMUST00000142864 Syne2-009 75818134-75880506 protein_coding
  ENSMUST00000143031 Syne2-001 75818318-76110926 protein_coding
  ENSMUST00000148324 Syne2-010 75852730-75880328 protein_coding
  ENSMUST00000148825 Syne2-016 76022300-76027815 protein_coding
  ENSMUST00000150317 Syne2-003 75818329-75908877 protein_coding
  ENSMUST00000151286 Syne2-011 76100901-76105992 retained_intron
  ENSMUST00000154509 Syne2-012 76081656-76095046 protein_coding
  ENSMUST00000154762 Syne2-015 76059674-76066516 retained_intron
  ENSMUST00000157033 Syne2-004 75818350-75905903 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000044217ENSMUST00000085280ENSMUST00000126903ENSMUST00000132161ENSMUST00000139204ENSMUST00000143031
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000044217 N/A N/A N/A N/A 0.634±0.00 N/A N/A N/A 0.191±0.01 N/A 0.214±0.02 N/A N/A N/A
ENSMUST00000085280 1.522±0.24 N/A 4.408±0.03 1.972±1.00 N/A N/A 0.916±0.25 N/A 0.212±0.06 N/A 0.897±0.15 50.616±26.35 2.896±2.06 7.049±0.00
ENSMUST00000126903 N/A N/A N/A 9.127±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 23.157±6.22 N/A
ENSMUST00000132161 10.418±0.57 8.070±0.53 8.515±1.21 8.587±3.97 7.092±2.18 14.427±1.16 5.624±0.41 10.324±1.28 1.261±0.49 23.220±1.98 1.409±0.46 48.999±6.72 3.383±0.87 4.316±0.60
ENSMUST00000139204 3.780±0.89 2.811±0.66 5.055±0.85 5.386±1.71 2.499±0.86 8.411±1.14 1.190±0.17 8.604±2.07 0.882±0.44 8.242±0.99 N/A 28.676±6.66 1.524±0.10 5.287±0.43
ENSMUST00000143031 1.344±0.46 0.574±0.09 1.153±0.24 0.869±0.49 0.696±0.12 1.304±0.19 0.713±0.09 2.189±0.38 0.228±0.11 2.512±0.31 0.282±0.06 8.438±3.58 0.799±0.33 0.886±0.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004WO CIL_0004WO_0002 CGP 12:75714248-76110926
CIL_00010O CIL_00010O_0002 CGP 12:75818134-76177259

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 IEA:IDA actin binding
GO:0005634 IEA nucleus
GO:0005635 IDA nuclear envelope
GO:0005640 IDA nuclear outer membrane
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005925 IEA focal adhesion
GO:0006998 IMP nuclear envelope organization
GO:0007097 IEA nuclear migration
GO:0007163 IMP establishment or maintenance of cell polarity
GO:0010761 IMP fibroblast migration
GO:0016021 IEA integral component of membrane
GO:0016235 IEA aggresome
GO:0016529 IEA sarcoplasmic reticulum
GO:0030016 IDA myofibril
GO:0030018 IDA Z disc
GO:0030335 IMP positive regulation of cell migration
GO:0031022 IMP nuclear migration along microfilament
GO:0031258 IEA lamellipodium membrane
GO:0031527 IEA filopodium membrane
GO:0031965 IDA nuclear membrane
GO:0031981 IEA nuclear lumen
GO:0034504 IMP protein localization to nucleus
GO:0034993 IEA SUN-KASH complex
GO:0045111 IEA intermediate filament cytoskeleton
GO:0051642 IMP centrosome localization
GO:0090286 IEA cytoskeletal anchoring at nuclear membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030107 syne2a spectrin repeat containing, nuclear envelope 2a protein_coding Danio_rerio
ENSDARG00000053484 syne2b spectrin repeat containing, nuclear envelope 2b protein_coding Danio_rerio
ENSG00000054654 SYNE2 spectrin repeat containing, nuclear envelope 2 protein_coding Homo_sapiens

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