C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transcription factor AP-2, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000021787 Tfap2a-201 ENSMUSG00000021359 10090 - 13:40715675-40730418 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonKidneyLungPlacentaTestisENSMUST00000021787
Transcript ID Bladder Brain Breast Colon Kidney Lung Placenta Testis
ENSMUST00000021787 0.068±0.00 2.451±1.65 1.198±0.73 0.022±0.01 0.619±0.25 0.391±0.27 0.487±0.34 0.128±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007NC CIL_0007NC_0002 UCNEbase 13:38708565-40726483
CIL_00097A CIL_00097A_0002 VISTA 13:40412299-41013499
CIL_00086X CIL_00086X_0002 VISTA 13:40425554-41028254
CIL_000382 CIL_000382_0002 CGP 13:40715675-40960891

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000987 IDA core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001843 IMP neural tube closure
GO:0002089 IMP lens morphogenesis in camera-type eye
GO:0003151 IMP outflow tract morphogenesis
GO:0003334 IGI keratinocyte development
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 TAS transcription factor complex
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0008285 IMP negative regulation of cell proliferation
GO:0009880 IMP embryonic pattern specification
GO:0010172 IMP embryonic body morphogenesis
GO:0014032 IMP neural crest cell development
GO:0021506 IMP anterior neuropore closure
GO:0021884 IMP forebrain neuron development
GO:0030335 IMP positive regulation of cell migration
GO:0035136 IMP forelimb morphogenesis
GO:0042059 IMP negative regulation of epidermal growth factor receptor signaling pathway
GO:0043524 IGI negative regulation of neuron apoptotic process
GO:0043588 IGI skin development
GO:0045664 IMP regulation of neuron differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048485 IGI sympathetic nervous system development
GO:0048596 IMP embryonic camera-type eye morphogenesis
GO:0048701 IMP embryonic cranial skeleton morphogenesis
GO:0048705 IMP skeletal system morphogenesis
GO:0048730 IMP epidermis morphogenesis
GO:0060235 IMP lens induction in camera-type eye
GO:0060325 IMP face morphogenesis
GO:0061303 IMP cornea development in camera-type eye
GO:0071711 IMP basement membrane organization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000082346 tfap2a-201 protein_coding Danio_rerio 7e-29 134
ENSDART00000082349 tfap2a-202 protein_coding Danio_rerio 7e-29 134
ENSDART00000082351 tfap2a-203 protein_coding Danio_rerio 7e-29 134
ENST00000319516 TFAP2A-003 protein_coding Homo_sapiens 0 2167
ENST00000379604 TFAP2A-201 protein_coding Homo_sapiens 0 2693
ENST00000379608 TFAP2A-005 protein_coding Homo_sapiens 0 2246
ENST00000379613 TFAP2A-001 protein_coding Homo_sapiens 0 2693
ENST00000393655 TFAP2B-001 protein_coding Homo_sapiens 0 272
ENST00000461628 TFAP2A-017 protein_coding Homo_sapiens 0 289
ENST00000462727 TFAP2A-014 processed_transcript Homo_sapiens 0 730
ENST00000464323 TFAP2A-006 retained_intron Homo_sapiens 0 640
ENST00000465858 TFAP2A-016 protein_coding Homo_sapiens 0 516
ENST00000466073 TFAP2A-010 protein_coding Homo_sapiens 0 1264
ENST00000473652 TFAP2A-013 processed_transcript Homo_sapiens 0 520
ENST00000474952 TFAP2A-012 retained_intron Homo_sapiens 0 833
ENST00000475264 TFAP2A-018 protein_coding Homo_sapiens 0 870
ENST00000478375 TFAP2A-002 retained_intron Homo_sapiens 0 1264
ENST00000482890 TFAP2A-007 protein_coding Homo_sapiens 0 2145
ENST00000488193 TFAP2A-008 nonsense_mediated_decay Homo_sapiens 0 1807
ENST00000489805 TFAP2A-011 nonsense_mediated_decay Homo_sapiens 0 2174
ENST00000490875 TFAP2A-004 processed_transcript Homo_sapiens 0 933
ENST00000497266 TFAP2A-015 processed_transcript Homo_sapiens 0 1186
ENST00000498450 TFAP2A-009 protein_coding Homo_sapiens 0 562

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