C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: RAB guanine nucleotide exchange factor (GEF) 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000119027 Rabgef1-004 ENSMUSG00000025340 10090 + 5:130187161-130208752 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005UP CIL_0005UP_0002 CGP 5:130144861-130214342
CIL_000256 CIL_000256_0002 CGP 5:130171798-130243765

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001933 IMP negative regulation of protein phosphorylation
GO:0002686 IMP negative regulation of leukocyte migration
GO:0003677 IEA DNA binding
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0008270 IEA zinc ion binding
GO:0016567 IDA protein ubiquitination
GO:0031982 IDA vesicle
GO:0033004 IMP negative regulation of mast cell activation
GO:0043305 IMP negative regulation of mast cell degranulation
GO:0046580 IMP negative regulation of Ras protein signal transduction
GO:0048261 IMP negative regulation of receptor-mediated endocytosis
GO:0050728 IMP negative regulation of inflammatory response
GO:0060368 IMP regulation of Fc receptor mediated stimulatory signaling pathway
GO:1900165 IMP negative regulation of interleukin-6 secretion
GO:1900235 IMP negative regulation of Kit signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000284957 RABGEF1-001 protein_coding Homo_sapiens 0 841
ENST00000380828 RABGEF1-201 protein_coding Homo_sapiens 0 841
ENST00000411606 GS1-124K5.2-003 transcribed_unprocessed_pseudogene Homo_sapiens 0 231
ENST00000428370 GS1-124K5.12-001 unprocessed_pseudogene Homo_sapiens 0 296
ENST00000437078 RABGEF1-202 protein_coding Homo_sapiens 0 444
ENST00000439720 RABGEF1-003 protein_coding Homo_sapiens 0 841
ENST00000442563 RABGEF1-005 protein_coding Homo_sapiens 0 230
ENST00000449786 AC005077.7-001 unprocessed_pseudogene Homo_sapiens 0 307
ENST00000450873 RABGEF1-002 protein_coding Homo_sapiens 0 841
ENST00000484547 RABGEF1-004 processed_transcript Homo_sapiens 0 483
ENST00000503687 KCTD7-004 nonsense_mediated_decay Homo_sapiens 0 483
ENST00000510829 RABGEF1-203 protein_coding Homo_sapiens 0 442
ENST00000607882 RABGEF1-007 nonsense_mediated_decay Homo_sapiens 0 444

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