C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: RAB guanine nucleotide exchange factor (GEF) 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000450873 RABGEF1-002 ENSG00000154710 9606 + 7:66740733-66809817 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastHeartKidneyLiverLungOvaryPlacentaTestisENST00000450873
Transcript ID Brain Breast Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000450873 1.979±0.00 2.300±0.00 1.136±0.27 1.972±0.00 2.673±1.64 2.726±0.89 3.285±0.85 2.969±0.36 9.129±0.93

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00024I CIL_00024I_0001 CGP 7:66205199-66811187
CIL_0005UP CIL_0005UP_0001 CGP 7:66628881-66811464
CIL_000256 CIL_000256_0001 CGP 7:66682164-66958551

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005515 IPI protein binding
GO:0005769 IMP early endosome
GO:0006612 IMP protein targeting to membrane
GO:0006897 IEA endocytosis
GO:0008270 IEA zinc ion binding
GO:0017112 IDA Rab guanyl-nucleotide exchange factor activity
GO:0017137 IPI Rab GTPase binding
GO:0032851 IDA positive regulation of Rab GTPase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000026390 Rabgef1-002 protein_coding Mus_musculus 0 1888
ENSMUST00000119797 Rabgef1-001 protein_coding Mus_musculus 0 1884
ENSMUST00000148264 Rabgef1-003 protein_coding Mus_musculus 0 944
ENSMUST00000119027 Rabgef1-004 protein_coding Mus_musculus 0 841
ENSMUST00000147493 Rabgef1-007 retained_intron Mus_musculus 0 501
ENSMUST00000143727 Rabgef1-005 retained_intron Mus_musculus 0 444

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