C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ryanodine receptor 2, cardiac
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000170156 Ryr2-202 ENSMUSG00000021313 10090 - 13:11553103-12106945 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000170156
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000170156 0.017±0.00 0.117±0.01 7.304±0.00 0.027±0.01 0.213±0.03 0.022±0.01 0.008±0.01 0.293±0.00 0.007±0.00 0.498±0.27 0.059±0.03 0.046±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000LI CIL_0000LI_0002 CGP 13:9875486-12106945

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003220 IMP left ventricular cardiac muscle tissue morphogenesis
GO:0003300 IMP cardiac muscle hypertrophy
GO:0005219 IDA ryanodine-sensitive calcium-release channel activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005516 IDA calmodulin binding
GO:0005790 IDA smooth endoplasmic reticulum
GO:0006816 IDA calcium ion transport
GO:0010460 IMP positive regulation of heart rate
GO:0014808 IMP release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0016020 IDA membrane
GO:0016021 IC integral component of membrane
GO:0016529 IDA sarcoplasmic reticulum
GO:0030018 IDA Z disc
GO:0030509 IDA BMP signaling pathway
GO:0031000 IDA response to caffeine
GO:0033017 IDA sarcoplasmic reticulum membrane
GO:0043234 ISO protein complex
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060401 IMP cytosolic calcium ion transport
GO:0070588 IMP calcium ion transmembrane transport
GO:0071313 IDA cellular response to caffeine
GO:0097159 IPI organic cyclic compound binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000147464 ryr3-001 protein_coding Danio_rerio 0 815
ENSDART00000149737 ryr2b-001 protein_coding Danio_rerio 0 793
ENSDART00000036015 ryr1b-201 protein_coding Danio_rerio 0 732
ENSDART00000026272 ryr2b-201 protein_coding Danio_rerio 0 691
ENSDART00000078464 CABZ01065506.1-201 protein_coding Danio_rerio 0.0003 55
ENST00000360064 RYR2-201 protein_coding Homo_sapiens 0 14750
ENST00000366574 RYR2-001 protein_coding Homo_sapiens 0 16760
ENST00000389232 RYR3-001 protein_coding Homo_sapiens 0 883
ENST00000415757 RYR3-002 protein_coding Homo_sapiens 0 883
ENST00000462585 RYR2-003 processed_transcript Homo_sapiens 0 351
ENST00000608590 RYR2-004 processed_transcript Homo_sapiens 0 1249
ENST00000609119 RYR2-006 processed_transcript Homo_sapiens 0 2228
ENST00000622037 RYR3-201 protein_coding Homo_sapiens 0 876

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