C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: kalirin, RhoGEF kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000240874 KALRN-005 ENSG00000160145 9606 + 3:124094681-124519850 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalLiverENST00000240874
Transcript ID Adrenal Liver
ENST00000240874 1.635±0.00 0.832±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005085 TAS guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0007165 TAS signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007399 ISS nervous system development
GO:0015629 TAS actin cytoskeleton
GO:0016192 TAS vesicle-mediated transport
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 ISS intracellular signal transduction
GO:0043065 TAS positive regulation of apoptotic process
GO:0043547 TAS positive regulation of GTPase activity
GO:0046872 IEA metal ion binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0070062 IDA extracellular vesicular exosome
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000089655 Kalrn-004 protein_coding Mus_musculus 0 7313
ENSMUST00000114960 Kalrn-001 protein_coding Mus_musculus 0 7149
ENSMUST00000114961 Kalrn-012 protein_coding Mus_musculus 0 6453
ENSMUST00000076810 Kalrn-011 protein_coding Mus_musculus 0 6451
ENSMUST00000142817 Kalrn-009 protein_coding Mus_musculus 0 6451
ENSMUST00000114953 Kalrn-005 protein_coding Mus_musculus 0 4769
ENSMUST00000114954 Kalrn-007 protein_coding Mus_musculus 0 4763
ENSMUST00000114949 Kalrn-003 protein_coding Mus_musculus 0 4265
ENSMUST00000151491 Kalrn-002 protein_coding Mus_musculus 0 3631
ENSMUST00000114947 Kalrn-018 protein_coding Mus_musculus 0 2876
ENSMUST00000137216 Kalrn-006 retained_intron Mus_musculus 0 1696
ENSDART00000114042 kalrna-201 protein_coding Danio_rerio 0 1354
ENSMUST00000090247 Trio-201 protein_coding Mus_musculus 0 1304
ENSDART00000087055 trioa-201 protein_coding Danio_rerio 0 1208
ENSDART00000144275 trioa-001 protein_coding Danio_rerio 0 1208
ENSDART00000000382 triob-201 protein_coding Danio_rerio 0 989
ENSMUST00000156668 Kalrn-017 processed_transcript Mus_musculus 0 481
ENSDART00000153785 triob-001 protein_coding Danio_rerio 0 459
ENSMUST00000132569 Kalrn-008 processed_transcript Mus_musculus 0 224
ENSMUST00000124430 Kalrn-019 processed_transcript Mus_musculus 7e-27 128

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