C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: COP9 signalosome subunit 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000299259 COPS2-003 ENSG00000166200 9606 - 15:49127350-49155661 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000299259
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000299259 14.159±0.00 4.469±0.00 5.668±0.18 7.485±1.95 15.541±11.76 9.348±5.96 9.700±4.70 7.842±1.19 13.981±9.56 16.643±12.63 12.728±3.50 6.889±0.57 16.147±4.41

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002PL CIL_0002PL_0001 CGP 15:48988476-49155661
CIL_0004QE CIL_0004QE_0002 CGP 15:49106068-49367869

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0003714 IEA transcription corepressor activity
GO:0004871 NAS signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0007165 NAS signal transduction
GO:0008180 IDA COP9 signalosome
GO:0008283 IEA cell proliferation
GO:0010388 IDA cullin deneddylation
GO:0030182 IEA neuron differentiation
GO:0035914 IEA skeletal muscle cell differentiation
GO:0045892 IEA negative regulation of transcription, DNA-templated

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000110463 Cops2-001 protein_coding Mus_musculus 0 2929
ENSMUST00000028635 Cops2-002 protein_coding Mus_musculus 0 2795
ENSMUST00000110462 Cops2-003 protein_coding Mus_musculus 0 1748
ENSDART00000006124 cops2-001 protein_coding Danio_rerio 0 987
ENSDART00000133872 cops2-002 protein_coding Danio_rerio 0 651
ENSMUST00000139343 Cops2-004 processed_transcript Mus_musculus 0 568
ENSMUST00000152683 Cops2-005 processed_transcript Mus_musculus 4e-35 154

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