C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: poly(A) binding protein, cytoplasmic 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000318607 PABPC1-001 ENSG00000070756 9606 - 8:100702916-100722712 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000318607
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000318607 45.071±0.00 2.848±0.00 3.147±0.00 14.546±0.00 19.383±0.00 1.517±0.00 7.373±0.00 13.655±0.00 13.916±0.00 1.501±0.00 92.820±38.44 47.715±14.25 92.233±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000184 TAS nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000288 TAS nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 TAS nuclear-transcribed mRNA poly(A) tail shortening
GO:0000398 IC mRNA splicing, via spliceosome
GO:0003676 IEA nucleic acid binding
GO:0003723 IEA RNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0005925 IDA focal adhesion
GO:0006378 TAS mRNA polyadenylation
GO:0006412 TAS translation
GO:0006413 TAS translational initiation
GO:0008022 IPI protein C-terminus binding
GO:0008143 IDA poly(A) binding
GO:0008266 IDA poly(U) RNA binding
GO:0008494 TAS translation activator activity
GO:0010467 TAS gene expression
GO:0010494 IDA cytoplasmic stress granule
GO:0016020 IDA membrane
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0030529 IDA ribonucleoprotein complex
GO:0031047 ISS gene silencing by RNA
GO:0036464 IDA cytoplasmic ribonucleoprotein granule
GO:0044267 TAS cellular protein metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045727 TAS positive regulation of translation
GO:0048255 TAS mRNA stabilization
GO:0060213 ISS positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0070062 IDA extracellular vesicular exosome
GO:0071013 IDA catalytic step 2 spliceosome
GO:1900153 ISS positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:2000623 IDA negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000001809 Pabpc1-001 protein_coding Mus_musculus 0 3895
ENSMUST00000063219 Pabpc2-001 protein_coding Mus_musculus 0 1938
ENSMUST00000162696 Gm16580-001 processed_pseudogene Mus_musculus 0 1491
ENSMUST00000156793 Pabpc1-006 processed_transcript Mus_musculus 0 1125
ENSMUST00000146327 Pabpc1-002 processed_transcript Mus_musculus 0 1040
ENSMUST00000057190 Pabpc6-201 protein_coding Mus_musculus 0 979
ENSMUST00000146577 Pabpc1-003 processed_transcript Mus_musculus 0 806
ENSMUST00000155116 Pabpc1-007 protein_coding Mus_musculus 0 531
ENSMUST00000147116 Pabpc1-004 processed_transcript Mus_musculus 0 459
ENSMUST00000142357 Pabpc1-005 processed_transcript Mus_musculus 0 446
ENSMUST00000119625 Gm11693-001 processed_pseudogene Mus_musculus 5e-21 108

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