C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: COP9 signalosome subunit 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000357849 COPS5-001 ENSG00000121022 9606 - 8:67043079-67062317 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000357849
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000357849 9.542±0.00 10.721±0.00 17.032±1.87 21.603±0.00 21.765±0.00 21.920±9.61 20.060±9.43 16.587±0.00 12.177±0.00 9.702±0.00 20.760±4.43 24.058±3.88 48.960±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003BD CIL_0003BD_0001 CGP 8:66946501-67056604
CIL_0003BC CIL_0003BC_0001 CGP 8:66964099-67083783
CIL_0003BF CIL_0003BF_0001 CGP 8:67043079-67196263

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000338 IMP protein deneddylation
GO:0003713 TAS transcription coactivator activity
GO:0003743 TAS translation initiation factor activity
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005852 TAS eukaryotic translation initiation factor 3 complex
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006412 TAS translation
GO:0006413 TAS translational initiation
GO:0006508 IEA proteolysis
GO:0008021 IDA synaptic vesicle
GO:0008180 IDA COP9 signalosome
GO:0008237 IMP metallopeptidase activity
GO:0010388 IDA cullin deneddylation
GO:0016579 IDA protein deubiquitination
GO:0030054 IEA cell junction
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046328 IDA regulation of JNK cascade
GO:0046872 IEA metal ion binding
GO:0051726 IEA regulation of cell cycle
GO:1990182 IDA exosomal secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000027050 Cops5-001 protein_coding Mus_musculus 0 1513
ENSMUST00000186528 Cops5-006 nonsense_mediated_decay Mus_musculus 0 1192
ENSMUST00000139578 Cops5-003 retained_intron Mus_musculus 0 989
ENSMUST00000188619 Cops5-005 protein_coding Mus_musculus 0 767
ENSMUST00000150509 Cops5-002 retained_intron Mus_musculus 0 582
ENSMUST00000190155 Cops5-007 nonsense_mediated_decay Mus_musculus 0 525

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