C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin, alpha 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000409080 ITGA6-004 ENSG00000091409 9606 + 2:172427789-172506282 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000409080
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000409080 32.748±0.00 5.360±0.00 3.957±0.00 6.485±0.00 8.966±0.61 15.044±1.97 5.023±0.00 12.187±0.00 2.484±0.61 7.892±0.14 8.250±4.29 22.508±6.64 13.498±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003IK CIL_0003IK_0002 CGP 2:172099439-172506282
CIL_0004K8 CIL_0004K8_0001 CGP 2:172427354-172608669

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005178 IEA integrin binding
GO:0005515 IPI protein binding
GO:0005604 IEA basement membrane
GO:0005886 IDA plasma membrane
GO:0005913 IEA cell-cell adherens junction
GO:0005925 IDA focal adhesion
GO:0007044 TAS cell-substrate junction assembly
GO:0007160 IEA cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0007596 TAS blood coagulation
GO:0008305 IEA integrin complex
GO:0009897 IEA external side of plasma membrane
GO:0009925 IEA basal plasma membrane
GO:0009986 IDA cell surface
GO:0010668 IEP ectodermal cell differentiation
GO:0010811 IEA positive regulation of cell-substrate adhesion
GO:0016323 IEA basolateral plasma membrane
GO:0016337 IEA single organismal cell-cell adhesion
GO:0022409 IEA positive regulation of cell-cell adhesion
GO:0030056 IEA hemidesmosome
GO:0030175 IEA filopodium
GO:0030198 TAS extracellular matrix organization
GO:0031581 TAS hemidesmosome assembly
GO:0031589 IMP cell-substrate adhesion
GO:0031668 IEA cellular response to extracellular stimulus
GO:0032403 IEA protein complex binding
GO:0033627 IEA cell adhesion mediated by integrin
GO:0034329 TAS cell junction assembly
GO:0034676 IEA integrin alpha6-beta4 complex
GO:0035878 IMP nail development
GO:0042327 IMP positive regulation of phosphorylation
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0043065 IGI positive regulation of apoptotic process
GO:0043236 IEA laminin binding
GO:0043588 IMP skin development
GO:0045178 IEA basal part of cell
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046847 IEA filopodium assembly
GO:0046872 IEA metal ion binding
GO:0048565 IMP digestive tract development
GO:0050873 IEA brown fat cell differentiation
GO:0050900 TAS leukocyte migration
GO:0071407 IEA cellular response to organic cyclic compound
GO:0072001 IMP renal system development
GO:0097186 IMP amelogenesis
GO:2001237 IMP negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000112101 Itga6-002 protein_coding Mus_musculus 0 3860
ENSMUST00000028522 Itga6-001 protein_coding Mus_musculus 0 3456
ENSMUST00000155249 Itga6-004 protein_coding Mus_musculus 0 2091
ENSMUST00000126787 Itga6-005 processed_transcript Mus_musculus 0 577
ENSMUST00000185205 RP24-331H14.2-001 processed_pseudogene Mus_musculus 0 464

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