C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: pre-B-cell leukemia homeobox 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000420696 PBX1-001 ENSG00000185630 9606 + 1:164559635-164851831 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBreastColonLiverLungOvaryPlacentaENST00000420696
Transcript ID Adrenal Bladder Breast Colon Liver Lung Ovary Placenta
ENST00000420696 1.886±0.00 1.698±0.00 2.824±0.00 2.086±0.00 7.961±7.70 2.582±1.56 6.503±5.72 1.280±0.40

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007M6 CIL_0007M6_0001 UCNEbase 1:164054328-164712505
CIL_0007US CIL_0007US_0001 VISTA 1:164334904-164936237
CIL_0008NA CIL_0008NA_0001 VISTA 1:164350801-164951927
CIL_0009AB CIL_0009AB_0001 VISTA 1:164368338-164969800
CIL_00096W CIL_00096W_0001 VISTA 1:164399355-165000586
CIL_00089R CIL_00089R_0001 VISTA 1:164403550-165004969
CIL_0008FU CIL_0008FU_0001 VISTA 1:164431022-165032285
CIL_00094F CIL_00094F_0001 VISTA 1:164536270-165137557

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001655 IEA urogenital system development
GO:0001658 IEA branching involved in ureteric bud morphogenesis
GO:0003677 IDA:IEA DNA binding
GO:0003700 NAS:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA:IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006694 IEA steroid biosynthetic process
GO:0007548 IEA sex differentiation
GO:0008134 IPI transcription factor binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0009887 IEA organ morphogenesis
GO:0009952 IEA anterior/posterior pattern specification
GO:0009954 IEA proximal/distal pattern formation
GO:0010971 IEA positive regulation of G2/M transition of mitotic cell cycle
GO:0030278 IEA regulation of ossification
GO:0030325 IEA adrenal gland development
GO:0030326 IEA embryonic limb morphogenesis
GO:0035162 IEA embryonic hemopoiesis
GO:0042127 IEA regulation of cell proliferation
GO:0043433 IDA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043565 IEA sequence-specific DNA binding
GO:0045665 IEA negative regulation of neuron differentiation
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0048536 IEA spleen development
GO:0048538 IEA thymus development
GO:0048568 IEA embryonic organ development
GO:0048706 IEA embryonic skeletal system development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000176540 Pbx1-002 protein_coding Mus_musculus 0 3049
ENSMUST00000072863 Pbx1-201 protein_coding Mus_musculus 0 1755
ENSMUST00000176790 Pbx1-004 protein_coding Mus_musculus 0 1755
ENSMUST00000188912 Pbx1-001 protein_coding Mus_musculus 0 1755
ENSMUST00000064438 Pbx1-005 protein_coding Mus_musculus 0 1279
ENSDART00000129503 pbx1b-203 protein_coding Danio_rerio 0 1048
ENSDART00000125538 pbx1b-202 protein_coding Danio_rerio 0 1048
ENSMUST00000176482 Pbx1-006 retained_intron Mus_musculus 0 955
ENSDART00000073947 pbx1a-203 protein_coding Danio_rerio 0 778
ENSDART00000122028 pbx1b-201 protein_coding Danio_rerio 0 756
ENSMUST00000176791 Pbx1-007 retained_intron Mus_musculus 0 676
ENSMUST00000097471 Pbx1-009 processed_transcript Mus_musculus 0 675
ENSDART00000038419 pbx1a-202 protein_coding Danio_rerio 0 616
ENSDART00000104683 pbx4-001 protein_coding Danio_rerio 0 562
ENSDART00000003750 pbx1a-201 protein_coding Danio_rerio 0 516
ENSDART00000100074 pbx3a-201 protein_coding Danio_rerio 0 457
ENSDART00000127078 PBX4 (2 of 2)-201 protein_coding Danio_rerio 0 388
ENSDART00000156935 pbx4-002 protein_coding Danio_rerio 0 309

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