C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: pre B cell leukemia homeobox 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000176540 Pbx1-002 ENSMUSG00000052534 10090 - 1:168153542-168431897 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000176540
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000176540 21.145±10.61 2.801±0.00 9.431±0.25 15.922±13.90 3.430±1.26 1.501±0.07 5.546±0.00 2.361±0.00 0.676±0.11 4.663±0.00 1.944±0.63 8.715±2.48 1.048±0.48 1.160±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00094F CIL_00094F_0002 VISTA 1:167868619-168470073
CIL_0008FU CIL_0008FU_0002 VISTA 1:167968572-168569856
CIL_00089R CIL_00089R_0002 VISTA 1:167994791-168596737
CIL_00096W CIL_00096W_0002 VISTA 1:167999764-168600980
CIL_0009AB CIL_0009AB_0002 VISTA 1:168027071-168628497
CIL_0008NA CIL_0008NA_0002 VISTA 1:168041597-168642833
CIL_0007US CIL_0007US_0002 VISTA 1:168057093-168658535

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001655 IMP urogenital system development
GO:0001658 IDA branching involved in ureteric bud morphogenesis
GO:0003677 IDA DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006694 IEA steroid biosynthetic process
GO:0007548 IEA sex differentiation
GO:0008134 IEA transcription factor binding
GO:0008284 IMP positive regulation of cell proliferation
GO:0009887 IMP organ morphogenesis
GO:0009952 IMP anterior/posterior pattern specification
GO:0009954 IMP proximal/distal pattern formation
GO:0010971 IMP positive regulation of G2/M transition of mitotic cell cycle
GO:0030278 IMP regulation of ossification
GO:0030325 IMP adrenal gland development
GO:0030326 IGI embryonic limb morphogenesis
GO:0035162 IMP embryonic hemopoiesis
GO:0042127 IMP regulation of cell proliferation
GO:0043433 IEA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043565 IDA sequence-specific DNA binding
GO:0045665 IGI negative regulation of neuron differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0048536 IGI spleen development
GO:0048538 IMP thymus development
GO:0048568 IMP embryonic organ development
GO:0048706 IMP embryonic skeletal system development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000129503 pbx1b-203 protein_coding Danio_rerio 0 1042
ENSDART00000125538 pbx1b-202 protein_coding Danio_rerio 0 1042
ENSDART00000073947 pbx1a-203 protein_coding Danio_rerio 0 817
ENSDART00000122028 pbx1b-201 protein_coding Danio_rerio 0 745
ENSDART00000038419 pbx1a-202 protein_coding Danio_rerio 0 632
ENSDART00000003750 pbx1a-201 protein_coding Danio_rerio 0 555
ENSDART00000104683 pbx4-001 protein_coding Danio_rerio 0 549
ENSDART00000100074 pbx3a-201 protein_coding Danio_rerio 0 438
ENSDART00000127078 PBX4 (2 of 2)-201 protein_coding Danio_rerio 0 399
ENSDART00000156935 pbx4-002 protein_coding Danio_rerio 0 331
ENST00000340699 PBX1-007 protein_coding Homo_sapiens 0 922
ENST00000367897 PBX1-002 protein_coding Homo_sapiens 0 1541
ENST00000375050 PBX2-001 protein_coding Homo_sapiens 0.000000000000002 90
ENST00000383270 PBX2-001 protein_coding Homo_sapiens 0.000000000000002 90
ENST00000420432 PBX2-001 protein_coding Homo_sapiens 0.000000000000002 90
ENST00000420696 PBX1-001 protein_coding Homo_sapiens 0 3049
ENST00000431537 PBX2-001 protein_coding Homo_sapiens 0.000000000000002 90
ENST00000433552 PBX2-001 protein_coding Homo_sapiens 0.000000000000002 90
ENST00000453487 PBX2-001 protein_coding Homo_sapiens 0.000000000000002 90
ENST00000453961 PBX2-001 protein_coding Homo_sapiens 0.000000000000002 90
ENST00000461053 PBX2-005 retained_intron Homo_sapiens 0.0000000000003 81
ENST00000461857 PBX2-005 retained_intron Homo_sapiens 0.0000000000003 81
ENST00000465089 PBX1-005 retained_intron Homo_sapiens 0 1301
ENST00000467023 PBX1-008 processed_transcript Homo_sapiens 1e-31 139
ENST00000468104 PBX1-004 processed_transcript Homo_sapiens 0 2154
ENST00000471428 PBX2-005 retained_intron Homo_sapiens 0.0000000000003 81
ENST00000479667 PBX2-005 retained_intron Homo_sapiens 0.0000000000003 81
ENST00000482110 PBX1-009 protein_coding Homo_sapiens 0 586
ENST00000485769 PBX1-006 protein_coding Homo_sapiens 0 466
ENST00000487027 PBX2-005 retained_intron Homo_sapiens 0.0000000000003 81
ENST00000491147 PBX2-005 retained_intron Homo_sapiens 0.0000000000003 81
ENST00000495300 PBX2-005 retained_intron Homo_sapiens 0.0000000000003 81
ENST00000496120 PBX1-016 processed_transcript Homo_sapiens 0 2206
ENST00000498497 PBX1-010 retained_intron Homo_sapiens 0 464
ENST00000540236 PBX1-201 protein_coding Homo_sapiens 0 2377
ENST00000558837 PBX1-019 protein_coding Homo_sapiens 0 638
ENST00000559240 PBX1-012 protein_coding Homo_sapiens 0 1279
ENST00000559560 PBX1-018 protein_coding Homo_sapiens 0 455
ENST00000559578 PBX1-013 protein_coding Homo_sapiens 0 710
ENST00000560469 PBX1-015 processed_transcript Homo_sapiens 0 2202
ENST00000560641 PBX1-017 protein_coding Homo_sapiens 0 2375
ENST00000612123 PBX1-202 protein_coding Homo_sapiens 0 1092

Loading