C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine phosphatase, receptor type, T
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196090 PTPRT 9606 - 20:42072752-43189970 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356100 PTPRT-004 42072752-43189733 protein_coding
  ENST00000373184 PTPRT-006 42072752-43189733 protein_coding
  ENST00000373187 PTPRT-002 42072752-43189733 protein_coding
  ENST00000373190 PTPRT-001 42072752-43189842 protein_coding
  ENST00000373193 PTPRT-009 42072774-43189917 protein_coding
  ENST00000373198 PTPRT-005 42072752-43189969 protein_coding
  ENST00000373201 PTPRT-007 42072752-43189970 protein_coding
  ENST00000485499 PTPRT-008 42885842-42966419 processed_transcript
  ENST00000612229 PTPRT-201 42072774-42472569 protein_coding
  ENST00000617474 PTPRT-010 42080879-43189917 nonsense_mediated_decay
  ENST00000618610 PTPRT-202 42080879-42472562 protein_coding
  ENST00000620410 PTPRT-203 42677866-42791467 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000356100ENST00000373184ENST00000373187ENST00000373190ENST00000373201ENST00000612229ENST00000617474ENST00000618610ENST00000620410
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000356100 N/A N/A N/A 2.416±0.00 N/A N/A N/A N/A N/A N/A N/A 0.005±0.00 N/A 0.524±0.00
ENST00000373184 N/A 0.037±0.00 N/A 0.965±0.00 N/A 0.086±0.00 N/A N/A N/A 0.570±0.00 N/A 0.376±0.37 0.266±0.09 N/A
ENST00000373187 N/A N/A N/A N/A N/A N/A 0.067±0.00 N/A N/A N/A N/A 0.003±0.00 0.143±0.00 N/A
ENST00000373190 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.178±0.00 N/A
ENST00000373201 N/A 0.038±0.00 N/A N/A 0.230±0.00 N/A N/A N/A N/A N/A N/A 0.005±0.00 N/A N/A
ENST00000612229 0.005±0.00 0.070±0.00 N/A 6.667±3.85 0.203±0.06 0.039±0.00 0.011±0.00 0.103±0.04 0.097±0.01 0.441±0.12 0.009±0.01 0.140±0.19 0.217±0.00 0.399±0.00
ENST00000617474 N/A N/A 0.077±0.00 N/A N/A N/A 0.040±0.00 N/A N/A N/A N/A N/A 0.398±0.00 N/A
ENST00000618610 0.038±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.264±0.00 N/A
ENST00000620410 N/A N/A N/A N/A 0.720±0.00 0.325±0.00 N/A 0.520±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004E5 CIL_0004E5_0001 CGP 20:41402101-43189970
CIL_0004E4 CIL_0004E4_0001 CGP 20:42072752-43464247

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005515 IEA protein binding
GO:0005886 IDA plasma membrane
GO:0006470 IEA protein dephosphorylation
GO:0007155 NAS cell adhesion
GO:0007156 IDA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007165 NAS signal transduction
GO:0007169 IMP transmembrane receptor protein tyrosine kinase signaling pathway
GO:0008013 IPI beta-catenin binding
GO:0009986 IDA cell surface
GO:0016020 IEA membrane
GO:0016021 NAS integral component of membrane
GO:0016311 IEA dephosphorylation
GO:0016790 IEA thiolester hydrolase activity
GO:0016791 IEA phosphatase activity
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0045294 IDA alpha-catenin binding
GO:0045295 IDA gamma-catenin binding
GO:0045296 IPI cadherin binding
GO:0051393 IEA alpha-actinin binding
GO:0070097 IPI delta-catenin binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086147 protein tyrosine phosphatase, receptor type, T protein_coding Danio_rerio
ENSMUSG00000053141 Ptprt protein tyrosine phosphatase, receptor type, T protein_coding Mus_musculus

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