C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: secreted acidic cysteine rich glycoprotein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000018737 Sparc-001 ENSMUSG00000018593 10090 - 11:55394500-55420080 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018737
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018737 188.755±108.31 600.293±52.54 522.189±56.26 23.892±7.87 199.307±60.99 66.005±11.71 31.281±2.49 19.465±5.35 185.022±28.14 31.809±11.23 165.772±67.83 257.921±62.83 27.732±4.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00025X CIL_00025X_0002 CGP 11:55250609-55420080
CIL_0007IC CIL_0007IC_0003 CGP 11:55394500-55461239

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001503 IEA ossification
GO:0001937 IEA negative regulation of endothelial cell proliferation
GO:0005518 IEA collagen binding
GO:0005604 IEA basement membrane
GO:0005615 IEA extracellular space
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0007165 IEA signal transduction
GO:0007507 IEA heart development
GO:0009629 IEA response to gravity
GO:0009986 IEA cell surface
GO:0010288 IEA response to lead ion
GO:0010595 IEA positive regulation of endothelial cell migration
GO:0016363 IEA nuclear matrix
GO:0016525 IEA negative regulation of angiogenesis
GO:0022604 IEA regulation of cell morphogenesis
GO:0030324 IEA lung development
GO:0031012 IDA extracellular matrix
GO:0031091 IEA platelet alpha granule
GO:0031092 IEA platelet alpha granule membrane
GO:0031988 IEA membrane-bounded vesicle
GO:0032496 IEA response to lipopolysaccharide
GO:0033591 IEA response to L-ascorbic acid
GO:0034097 IEA response to cytokine
GO:0042060 IEA wound healing
GO:0042127 IGI regulation of cell proliferation
GO:0043434 IEA response to peptide hormone
GO:0045471 IEA response to ethanol
GO:0046686 IEA response to cadmium ion
GO:0048839 IEA inner ear development
GO:0050840 IDA extracellular matrix binding
GO:0051384 IEA response to glucocorticoid
GO:0051591 IEA response to cAMP
GO:0051592 IEA response to calcium ion
GO:0060348 IMP bone development
GO:0071363 IDA cellular response to growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000039660 sparc-001 protein_coding Danio_rerio 0 619
ENSDART00000135627 sparc-002 protein_coding Danio_rerio 0 496
ENSDART00000141304 sparc-004 protein_coding Danio_rerio 0 267
ENSDART00000142572 sparc-005 retained_intron Danio_rerio 0 237
ENST00000231061 SPARC-001 protein_coding Homo_sapiens 0 1371
ENST00000520687 SPARC-002 retained_intron Homo_sapiens 0 680
ENST00000521327 SPARC-003 retained_intron Homo_sapiens 0 252
ENST00000521569 SPARC-005 protein_coding Homo_sapiens 0 678
ENST00000522348 SPARC-004 protein_coding Homo_sapiens 3e-35 152
ENST00000524277 SPARC-006 retained_intron Homo_sapiens 0 525
ENST00000537849 SPARC-009 processed_transcript Homo_sapiens 0 211
ENST00000538026 SPARC-008 protein_coding Homo_sapiens 0 736
ENST00000539687 SPARC-007 protein_coding Homo_sapiens 0 377
ENST00000620972 SPARC-201 protein_coding Homo_sapiens 0 1254

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