C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: secreted protein, acidic, cysteine-rich (osteonectin)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000231061 SPARC-001 ENSG00000113140 9606 - 5:151661096-151687165 protein_coding

Homo sapiens EnsemblGRCh38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000231061
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000231061 4.687±0.00 13.008±0.00 27.815±0.00 9.551±0.00 9.446±0.00 7.130±0.00 25.349±0.00 14.045±0.00 6.057±0.00 47.682±19.37 147.848±1.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00025X CIL_00025X_0001 CGP 5:151504093-151687165
CIL_0007IC CIL_0007IC_0002 CGP 5:151661096-151772532

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001503 IEA ossification
GO:0001937 IDA negative regulation of endothelial cell proliferation
GO:0002576 TAS platelet degranulation
GO:0005509 IDA:IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005518 IDA collagen binding
GO:0005576 NAS extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005604 IEA basement membrane
GO:0005615 IEA extracellular space
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0007165 IEA signal transduction
GO:0007507 IEA heart development
GO:0007596 TAS blood coagulation
GO:0009629 IEA response to gravity
GO:0009986 IDA cell surface
GO:0010288 IEA response to lead ion
GO:0010595 IDA positive regulation of endothelial cell migration
GO:0016363 IDA nuclear matrix
GO:0016525 IDA negative regulation of angiogenesis
GO:0022604 IDA regulation of cell morphogenesis
GO:0030168 TAS platelet activation
GO:0030198 TAS extracellular matrix organization
GO:0030324 IEA lung development
GO:0031012 IEA extracellular matrix
GO:0031091 IDA platelet alpha granule
GO:0031092 IDA platelet alpha granule membrane
GO:0031093 TAS platelet alpha granule lumen
GO:0031988 IEA membrane-bounded vesicle
GO:0032496 IEA response to lipopolysaccharide
GO:0033591 IEA response to L-ascorbic acid
GO:0034097 IEA response to cytokine
GO:0042060 IEA wound healing
GO:0042127 IEA regulation of cell proliferation
GO:0043434 IEA response to peptide hormone
GO:0045471 IEA response to ethanol
GO:0046686 IEA response to cadmium ion
GO:0048839 IEA inner ear development
GO:0050840 IEA extracellular matrix binding
GO:0051384 IEA response to glucocorticoid
GO:0051591 IEA response to cAMP
GO:0051592 IEA response to calcium ion
GO:0060348 IEA bone development
GO:0071363 IEA cellular response to growth factor stimulus
GO:0071682 TAS endocytic vesicle lumen

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000018737 Sparc-001 protein_coding Mus_musculus 0 1371
ENSMUST00000108858 Sparc-002 protein_coding Mus_musculus 0 1293
ENSMUST00000130642 Sparc-005 processed_transcript Mus_musculus 0 798
ENSMUST00000141530 Sparc-003 protein_coding Mus_musculus 0 693
ENSMUST00000123775 Sparc-006 processed_transcript Mus_musculus 0 680
ENSDART00000039660 sparc-001 protein_coding Danio_rerio 0 571
ENSDART00000135627 sparc-002 protein_coding Danio_rerio 0 436
ENSDART00000141304 sparc-004 protein_coding Danio_rerio 0 213
ENSDART00000142572 sparc-005 retained_intron Danio_rerio 0 191
ENSMUST00000125787 Sparc-004 processed_transcript Mus_musculus 5e-36 158

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