C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: secreted protein, acidic, cysteine-rich (osteonectin)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000620972 SPARC-201 ENSG00000113140 9606 - 5:151661100-151685660 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; OvaryPlacentaTestisENST00000620972
Transcript ID Ovary Placenta Testis
ENST00000620972 58.807±10.75 323.088±0.00 86.098±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00025X CIL_00025X_0001 CGP 5:151504093-151687165
CIL_0007IC CIL_0007IC_0002 CGP 5:151661096-151772532

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001937 IDA negative regulation of endothelial cell proliferation
GO:0002576 TAS platelet degranulation
GO:0005509 IDA:IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005518 IDA collagen binding
GO:0005576 NAS extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005604 IEA basement membrane
GO:0005737 IDA cytoplasm
GO:0007165 IEA signal transduction
GO:0007596 TAS blood coagulation
GO:0009986 IDA cell surface
GO:0010595 IDA positive regulation of endothelial cell migration
GO:0016363 IDA nuclear matrix
GO:0016525 IDA negative regulation of angiogenesis
GO:0022604 IDA regulation of cell morphogenesis
GO:0030168 TAS platelet activation
GO:0030198 TAS extracellular matrix organization
GO:0031091 IDA platelet alpha granule
GO:0031092 IDA platelet alpha granule membrane
GO:0031093 TAS platelet alpha granule lumen
GO:0071682 TAS endocytic vesicle lumen

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000018737 Sparc-001 protein_coding Mus_musculus 0 1254
ENSMUST00000108858 Sparc-002 protein_coding Mus_musculus 0 1253
ENSMUST00000130642 Sparc-005 processed_transcript Mus_musculus 0 798
ENSMUST00000123775 Sparc-006 processed_transcript Mus_musculus 0 680
ENSMUST00000141530 Sparc-003 protein_coding Mus_musculus 0 651
ENSDART00000039660 sparc-001 protein_coding Danio_rerio 0 571
ENSDART00000135627 sparc-002 protein_coding Danio_rerio 0 436
ENSDART00000141304 sparc-004 protein_coding Danio_rerio 0 213
ENSDART00000142572 sparc-005 retained_intron Danio_rerio 0 191
ENSMUST00000125787 Sparc-004 processed_transcript Mus_musculus 8e-24 117

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