C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: zinc finger E-box binding homeobox 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000025081 Zeb1-001 ENSMUSG00000024238 10090 + 18:5591860-5775467 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025081
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025081 7.993±2.70 2.705±0.00 7.067±1.98 10.000±6.23 6.535±2.01 1.556±0.37 6.263±0.24 2.118±0.85 2.070±1.14 8.594±0.98 4.888±1.10 6.884±2.72 2.031±0.79 1.886±0.52

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000R6 CIL_0000R6_0002 CGP 18:5210031-5775467
CIL_0000R1 CIL_0000R1_0002 CGP 18:5591860-6136098

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0003682 IDA chromatin binding
GO:0003690 IEA double-stranded DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0007389 IMP pattern specification process
GO:0007417 IGI central nervous system development
GO:0008134 IPI transcription factor binding
GO:0008285 IMP negative regulation of cell proliferation
GO:0010464 IMP regulation of mesenchymal cell proliferation
GO:0014823 IEA response to activity
GO:0017015 IGI regulation of transforming growth factor beta receptor signaling pathway
GO:0030857 IMP negative regulation of epithelial cell differentiation
GO:0030900 IEA forebrain development
GO:0031667 IEA response to nutrient levels
GO:0033081 IMP regulation of T cell differentiation in thymus
GO:0045666 IDA positive regulation of neuron differentiation
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048513 IMP organ development
GO:0048596 IMP embryonic camera-type eye morphogenesis
GO:0048598 IGI embryonic morphogenesis
GO:0048704 IMP embryonic skeletal system morphogenesis
GO:0048752 IMP semicircular canal morphogenesis
GO:0051150 IMP regulation of smooth muscle cell differentiation
GO:0051216 IMP cartilage development
GO:0070888 IDA E-box binding
GO:0071230 IDA cellular response to amino acid stimulus
GO:0071560 IEA cellular response to transforming growth factor beta stimulus
GO:0090103 IMP cochlea morphogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000047724 zeb1b-001 protein_coding Danio_rerio 0 339
ENST00000320985 ZEB1-018 protein_coding Homo_sapiens 0 3155
ENST00000361642 ZEB1-201 protein_coding Homo_sapiens 0 3155
ENST00000424869 ZEB1-004 protein_coding Homo_sapiens 0 651
ENST00000437844 ZEB1-001 nonsense_mediated_decay Homo_sapiens 0 3155
ENST00000446923 ZEB1-202 protein_coding Homo_sapiens 0 3155
ENST00000488625 ZEB1-005 retained_intron Homo_sapiens 0 3155
ENST00000515048 ZEB2P1-001 transcribed_processed_pseudogene Homo_sapiens 0 189
ENST00000542815 ZEB1-016 protein_coding Homo_sapiens 0 3155
ENST00000542879 ZEB1-017 retained_intron Homo_sapiens 0 3155
ENST00000557827 ZEB1-013 retained_intron Homo_sapiens 0 481
ENST00000558440 ZEB1-003 protein_coding Homo_sapiens 0 769
ENST00000558655 ZEB1-009 retained_intron Homo_sapiens 0 2571
ENST00000558863 ZEB1-019 retained_intron Homo_sapiens 0 1452
ENST00000559476 ZEB1-012 protein_coding Homo_sapiens 0 669
ENST00000559496 ZEB1-011 retained_intron Homo_sapiens 0 481
ENST00000559858 ZEB1-015 processed_transcript Homo_sapiens 0 2571
ENST00000560196 ZEB1-007 retained_intron Homo_sapiens 2e-20 104
ENST00000560721 ZEB1-002 protein_coding Homo_sapiens 0 3518
ENST00000561061 ZEB1-010 processed_transcript Homo_sapiens 0 532
ENST00000561212 ZEB1-020 protein_coding Homo_sapiens 0 1452
ENST00000561304 ZEB1-008 retained_intron Homo_sapiens 0 501
ENST00000606161 ZEB1-022 processed_transcript Homo_sapiens 0.000000004 66
ENST00000606671 ZEB1-024 processed_transcript Homo_sapiens 0.000000000002 77

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