C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SMAD family member 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000154323 Smad3-002 ENSMUSG00000032402 10090 - 9:63654799-63711969 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LiverENSMUST00000154323
Transcript ID Liver
ENSMUST00000154323 2.062±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007L5 CIL_0007L5_0002 UCNEbase 9:63176391-63881226
CIL_0008V3 CIL_0008V3_0002 VISTA 9:63223990-63824533
CIL_0008R9 CIL_0008R9_0002 VISTA 9:63580198-64181507

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001501 IGI skeletal system development
GO:0001701 IGI in utero embryonic development
GO:0001707 IMP mesoderm formation
GO:0001756 IMP somitogenesis
GO:0001889 IGI liver development
GO:0001947 IGI heart looping
GO:0002076 IGI osteoblast development
GO:0002520 IGI immune system development
GO:0003682 IDA chromatin binding
GO:0003690 IDA double-stranded DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005518 IPI collagen binding
GO:0005634 IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0005886 IDA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0007179 IDA transforming growth factor beta receptor signaling pathway
GO:0007369 IGI gastrulation
GO:0007492 IGI endoderm development
GO:0009880 IGI embryonic pattern specification
GO:0016202 IDA regulation of striated muscle tissue development
GO:0017015 IDA regulation of transforming growth factor beta receptor signaling pathway
GO:0030878 IGI thyroid gland development
GO:0045668 IGI negative regulation of osteoblast differentiation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048340 IMP paraxial mesoderm morphogenesis
GO:0048589 IGI developmental growth
GO:0048617 IGI embryonic foregut morphogenesis
GO:0048701 IGI embryonic cranial skeleton morphogenesis
GO:0050678 IMP regulation of epithelial cell proliferation
GO:0051098 IDA regulation of binding
GO:0060039 IGI pericardium development
GO:0060395 IGI SMAD protein signal transduction
GO:0070306 IMP lens fiber cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000128579 smad2-202 protein_coding Danio_rerio 0 381
ENSDART00000044756 smad2-201 protein_coding Danio_rerio 0 381
ENSDART00000147653 smad2-002 protein_coding Danio_rerio 0 381
ENSDART00000121892 smad2-001 protein_coding Danio_rerio 0 381
ENSDART00000143608 smad2-004 protein_coding Danio_rerio 4e-26 122
ENST00000327367 SMAD3-001 protein_coding Homo_sapiens 0 970
ENST00000439724 SMAD3-003 protein_coding Homo_sapiens 0 970
ENST00000537194 SMAD3-004 protein_coding Homo_sapiens 0 525
ENST00000540846 SMAD3-002 protein_coding Homo_sapiens 0 972
ENST00000558428 SMAD3-009 protein_coding Homo_sapiens 0 468
ENST00000558739 SMAD3-014 protein_coding Homo_sapiens 0 405
ENST00000558827 SMAD3-008 protein_coding Homo_sapiens 0 525
ENST00000558894 SMAD3-013 protein_coding Homo_sapiens 0 937
ENST00000559092 SMAD3-015 protein_coding Homo_sapiens 0 195
ENST00000559460 SMAD3-012 protein_coding Homo_sapiens 0 549
ENST00000559937 SMAD3-010 retained_intron Homo_sapiens 0 658
ENST00000560175 SMAD3-016 protein_coding Homo_sapiens 0 658

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