C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SRY (sex determining region Y)-box 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000451604 SOX5-002 ENSG00000134532 9606 - 12:23532352-23949703 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LungOvaryPlacentaENST00000451604
Transcript ID Lung Ovary Placenta
ENST00000451604 0.498±0.00 0.164±0.00 0.436±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006Y0 CIL_0006Y0_0002 CGP 12:22625075-23951032
CIL_0007NR CIL_0007NR_0001 UCNEbase 12:22767069-24538480
CIL_0004XB CIL_0004XB_0001 CGP 12:23529500-24949459

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001701 IEA in utero embryonic development
GO:0003677 IEA DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0021953 IEA central nervous system neuron differentiation
GO:0032332 IDA positive regulation of chondrocyte differentiation
GO:0044212 IEA transcription regulatory region DNA binding
GO:0044798 IEA nuclear transcription factor complex
GO:0045165 IEA cell fate commitment
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0048709 IEA oligodendrocyte differentiation
GO:0051216 IEA cartilage development
GO:0060164 IEA regulation of timing of neuron differentiation
GO:0061036 IDA positive regulation of cartilage development
GO:0071560 IDA cellular response to transforming growth factor beta stimulus
GO:2000741 IDA positive regulation of mesenchymal stem cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000038815 Sox5-001 protein_coding Mus_musculus 0 3640
ENSMUST00000170367 Sox5-201 protein_coding Mus_musculus 0 1908
ENSMUST00000111749 Sox5-005 protein_coding Mus_musculus 0 1908
ENSMUST00000077160 Sox5-002 protein_coding Mus_musculus 0 1908
ENSMUST00000111748 Sox5-003 protein_coding Mus_musculus 0 1908
ENSMUST00000141102 Sox5-009 retained_intron Mus_musculus 0 1314
ENSMUST00000142294 Sox5-006 retained_intron Mus_musculus 0 1234
ENSMUST00000129050 Sox5-007 retained_intron Mus_musculus 0 1177
ENSMUST00000111746 Sox5-004 processed_transcript Mus_musculus 0 815
ENSMUST00000144289 Sox5-013 protein_coding Mus_musculus 0 808
ENSMUST00000124233 Sox5-010 protein_coding Mus_musculus 0 662
ENSMUST00000150087 Sox5-011 retained_intron Mus_musculus 0 564
ENSDART00000100998 sox6-201 protein_coding Danio_rerio 0 270
ENSDART00000150068 sox6-001 protein_coding Danio_rerio 0 270
ENSMUST00000149451 Sox5-008 processed_transcript Mus_musculus 0 268
ENSMUST00000139478 Sox5-012 processed_transcript Mus_musculus 0 233
ENSDART00000006737 sox5-201 protein_coding Danio_rerio 2e-35 156
ENSDART00000134595 sox5-001 protein_coding Danio_rerio 3e-33 148

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