C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: collagen, type I, alpha 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164692 COL1A2 9606 + 7:94394561-94431232 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000297268 COL1A2-001 94394561-94431232 protein_coding
  ENST00000461525 COL1A2-005 94417772-94421400 retained_intron
  ENST00000464916 COL1A2-003 94427312-94430367 retained_intron
  ENST00000467931 COL1A2-006 94419453-94421046 retained_intron
  ENST00000469732 COL1A2-008 94423988-94425787 retained_intron
  ENST00000473573 COL1A2-007 94414220-94422040 retained_intron
  ENST00000478215 COL1A2-009 94425270-94426729 retained_intron
  ENST00000481570 COL1A2-002 94422471-94430688 retained_intron
  ENST00000488121 COL1A2-011 94426510-94427492 retained_intron
  ENST00000488298 COL1A2-012 94413709-94416810 retained_intron
  ENST00000492110 COL1A2-010 94426783-94427507 retained_intron
  ENST00000497316 COL1A2-004 94417464-94423118 retained_intron
  ENST00000620463 COL1A2-201 94394914-94430703 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000297268ENST00000473573ENST00000497316ENST00000620463
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000297268 12.899±0.00 18.811±0.00 2.095±0.00 0.492±0.06 58.405±5.26 13.454±1.61 5.100±0.44 12.889±0.00 1.887±0.00 13.803±3.56 3.415±0.00 132.611±101.36 114.140±32.23 36.541±14.37
ENST00000473573 N/A N/A 9.120±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000497316 N/A N/A N/A 1.496±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000620463 80.291±0.00 96.884±0.00 3.734±0.00 1.538±0.87 152.479±64.49 46.730±17.62 21.229±14.13 24.541±19.38 37.950±26.02 61.967±40.02 9.935±6.24 258.471±194.71 232.823±65.08 90.358±60.99

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006DY CIL_0006DY_0001 CGP 7:93962762-94431232
CIL_00082O CIL_00082O_0001 VISTA 7:94046650-94649568
CIL_0007XR CIL_0007XR_0001 VISTA 7:94067785-94669696
CIL_00095G CIL_00095G_0001 VISTA 7:94074791-94676705
CIL_0008ZR CIL_0008ZR_0001 VISTA 7:94144032-94745602
CIL_0004SO CIL_0004SO_0002 CGP 7:94394561-94557019

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 IMP skeletal system development
GO:0001568 IMP blood vessel development
GO:0005201 NAS:IEA extracellular matrix structural constituent
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005581 IEA collagen trimer
GO:0005584 IMP collagen type I trimer
GO:0005615 IDA extracellular space
GO:0005788 TAS endoplasmic reticulum lumen
GO:0007179 IDA transforming growth factor beta receptor signaling pathway
GO:0007266 IDA Rho protein signal transduction
GO:0007596 TAS blood coagulation
GO:0008217 IMP regulation of blood pressure
GO:0022617 TAS extracellular matrix disassembly
GO:0030168 TAS platelet activation
GO:0030198 TAS extracellular matrix organization
GO:0030199 IMP collagen fibril organization
GO:0030574 TAS collagen catabolic process
GO:0030674 IMP protein binding, bridging
GO:0031012 IDA extracellular matrix
GO:0042476 NAS odontogenesis
GO:0042802 IDA identical protein binding
GO:0043589 IMP skin morphogenesis
GO:0046332 IEA SMAD binding
GO:0046872 IEA metal ion binding
GO:0048407 IDA platelet-derived growth factor binding
GO:0050900 TAS leukocyte migration
GO:0070062 IDA extracellular vesicular exosome
GO:0070208 IEA protein heterotrimerization
GO:0071230 IEA cellular response to amino acid stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020007 col1a2 collagen, type I, alpha 2 protein_coding Danio_rerio
ENSMUSG00000029661 Col1a2 collagen, type I, alpha 2 protein_coding Mus_musculus

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