C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SLIT-ROBO Rho GTPase activating protein 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000097588 Srgap2-001 ENSMUSG00000026425 10090 - 1:131285251-131527347 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000097588
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000097588 2.919±0.03 1.922±0.45 1.094±0.00 3.056±1.05 3.035±1.38 1.427±0.67 1.638±0.49 1.823±0.53 1.104±0.92 5.088±1.36 0.927±0.22 2.904±1.01 3.147±3.37 1.378±0.50

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005VZ CIL_0005VZ_0002 CGP 1:131254343-131527352
CIL_00012Y CIL_00012Y_0003 CGP 1:131285251-131539872

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005634 IEA nucleus
GO:0005743 IDA mitochondrial inner membrane
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0007165 IEA signal transduction
GO:0014069 IDA postsynaptic density
GO:0021816 IMP extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration
GO:0030054 IEA cell junction
GO:0030675 IDA Rac GTPase activator activity
GO:0032855 IDA positive regulation of Rac GTPase activity
GO:0042803 IDA protein homodimerization activity
GO:0044327 ISS dendritic spine head
GO:0045211 IDA postsynaptic membrane
GO:0045335 IDA phagocytic vesicle
GO:0046847 IDA filopodium assembly
GO:0048365 IDA Rac GTPase binding
GO:0048812 IMP neuron projection morphogenesis
GO:0051014 ISS actin filament severing
GO:0060996 IMP dendritic spine development
GO:2001223 ISS negative regulation of neuron migration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000045391 srgap2a-201 protein_coding Danio_rerio 0 1253
ENSDART00000103865 srgap2a-001 protein_coding Danio_rerio 0 1253
ENST00000304465 SRGAP2C-201 protein_coding Homo_sapiens 0 1254
ENST00000360413 SRGAP3-002 protein_coding Homo_sapiens 0 490
ENST00000367123 SRGAP2C-001 protein_coding Homo_sapiens 0 2265
ENST00000383836 SRGAP3-001 protein_coding Homo_sapiens 0 307
ENST00000412759 SRGAP2C-003 processed_transcript Homo_sapiens 0 294
ENST00000419187 SRGAP2-201 protein_coding Homo_sapiens 0 1266
ENST00000433332 SRGAP3-010 processed_transcript Homo_sapiens 0 274
ENST00000463366 SRGAP2B-004 processed_transcript Homo_sapiens 0 279
ENST00000467933 SRGAP2B-002 processed_transcript Homo_sapiens 0 294
ENST00000470951 SRGAP3-005 retained_intron Homo_sapiens 0.000000000000001 90
ENST00000480750 SRGAP3-009 processed_transcript Homo_sapiens 3e-16 90
ENST00000485983 SRGAP3-004 retained_intron Homo_sapiens 0 307
ENST00000494534 SRGAP2B-003 processed_transcript Homo_sapiens 0 276
ENST00000572793 SRGAP2-011 protein_coding Homo_sapiens 0 327
ENST00000573034 SRGAP2-001 protein_coding Homo_sapiens 0 5009
ENST00000579225 SRGAP2-007 protein_coding Homo_sapiens 0 752
ENST00000603575 SRGAP2-009 processed_transcript Homo_sapiens 0 276
ENST00000603708 SRGAP2-008 processed_transcript Homo_sapiens 0 276
ENST00000604010 SRGAP2-015 protein_coding Homo_sapiens 0 682
ENST00000604133 SRGAP2-012 processed_transcript Homo_sapiens 0 667
ENST00000604247 SRGAP2-005 retained_intron Homo_sapiens 0 257
ENST00000604419 SRGAP2-013 retained_intron Homo_sapiens 0 545
ENST00000604423 SRGAP2-006 retained_intron Homo_sapiens 0 405
ENST00000604925 SRGAP2-014 protein_coding Homo_sapiens 0 974
ENST00000605242 SRGAP2-010 processed_transcript Homo_sapiens 0 582
ENST00000605476 SRGAP2-004 protein_coding Homo_sapiens 0 1890
ENST00000605551 SRGAP2D-001 unprocessed_pseudogene Homo_sapiens 0 1254
ENST00000605610 SRGAP2-002 protein_coding Homo_sapiens 0 3446
ENST00000612199 SRGAP2B-001 protein_coding Homo_sapiens 0 2261
ENST00000613462 SRGAP2C-004 processed_transcript Homo_sapiens 0 276
ENST00000617209 SRGAP2C-002 processed_transcript Homo_sapiens 0 279
ENST00000618999 SRGAP3-201 protein_coding Homo_sapiens 0 274
ENST00000619678 SRGAP2B-201 protein_coding Homo_sapiens 0 1260
ENST00000621582 SRGAP2B-005 nonsense_mediated_decay Homo_sapiens 0 568
ENST00000624686 SRGAP2-003 TEC Homo_sapiens 0 514
ENST00000624873 SRGAP2-016 protein_coding Homo_sapiens 0 4996

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