C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000122053 Cacna1a-002 ENSMUSG00000034656 10090 + 8:84415377-84640063 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENSMUST00000122053
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENSMUST00000122053 0.789±0.37 9.203±0.00 0.360±0.00 0.812±0.20 0.126±0.04 0.094±0.00 0.061±0.03 0.157±0.04 0.095±0.00 1.419±0.59 1.060±0.20

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006KV CIL_0006KV_0002 CGP 8:84388440-84662852

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000096 IMP sulfur amino acid metabolic process
GO:0003677 IEA DNA binding
GO:0005245 IMP voltage-gated calcium channel activity
GO:0005515 IPI protein binding
GO:0005891 IDA voltage-gated calcium channel complex
GO:0006006 IMP glucose metabolic process
GO:0006816 IMP calcium ion transport
GO:0007204 IDA positive regulation of cytosolic calcium ion concentration
GO:0007214 IMP gamma-aminobutyric acid signaling pathway
GO:0007268 IMP synaptic transmission
GO:0007270 IMP neuron-neuron synaptic transmission
GO:0007274 IMP neuromuscular synaptic transmission
GO:0007416 IMP synapse assembly
GO:0007628 IMP adult walking behavior
GO:0008331 IMP high voltage-gated calcium channel activity
GO:0014051 IMP gamma-aminobutyric acid secretion
GO:0014056 IMP regulation of acetylcholine secretion, neurotransmission
GO:0016049 IMP cell growth
GO:0017156 IMP calcium ion-dependent exocytosis
GO:0017158 IDA regulation of calcium ion-dependent exocytosis
GO:0019226 IMP transmission of nerve impulse
GO:0021522 IMP spinal cord motor neuron differentiation
GO:0021590 IMP cerebellum maturation
GO:0021679 IMP cerebellar molecular layer development
GO:0021680 IMP cerebellar Purkinje cell layer development
GO:0021702 IMP cerebellar Purkinje cell differentiation
GO:0021750 IMP vestibular nucleus development
GO:0021953 IMP central nervous system neuron differentiation
GO:0030425 IDA dendrite
GO:0030644 IMP cellular chloride ion homeostasis
GO:0032353 IMP negative regulation of hormone biosynthetic process
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035249 IMP synaptic transmission, glutamatergic
GO:0042133 IMP neurotransmitter metabolic process
GO:0042391 IMP regulation of membrane potential
GO:0042445 IMP hormone metabolic process
GO:0043025 IDA neuronal cell body
GO:0043113 IMP receptor clustering
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0048265 IMP response to pain
GO:0048266 IMP behavioral response to pain
GO:0048791 IMP calcium ion-dependent exocytosis of neurotransmitter
GO:0048813 IMP dendrite morphogenesis
GO:0050770 IMP regulation of axonogenesis
GO:0050877 IMP neurological system process
GO:0050883 IMP musculoskeletal movement, spinal reflex action
GO:0050885 IMP neuromuscular process controlling balance
GO:0050905 IGI neuromuscular process
GO:0051899 IMP membrane depolarization
GO:0060024 IMP rhythmic synaptic transmission
GO:0070509 IBA calcium ion import
GO:0070588 IEA calcium ion transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000150130 cacna1ab-001 protein_coding Danio_rerio 0 1321
ENSDART00000008139 cacna1ab-201 protein_coding Danio_rerio 0 1279
ENSDART00000089967 cacna1bb-201 protein_coding Danio_rerio 0 922
ENSDART00000132142 cacna1bb-001 protein_coding Danio_rerio 0 375
ENSDART00000089971 cacna1r-201 protein_coding Danio_rerio 0 215
ENSDART00000132899 cacna1r-002 protein_coding Danio_rerio 0 215
ENST00000360228 CACNA1A-001 protein_coding Homo_sapiens 0 4564
ENST00000573710 CACNA1A-002 protein_coding Homo_sapiens 0 4693
ENST00000573891 CACNA1A-004 nonsense_mediated_decay Homo_sapiens 0 582
ENST00000574822 CACNA1A-003 processed_transcript Homo_sapiens 0 1018
ENST00000585802 CACNA1A-012 protein_coding Homo_sapiens 0 2911
ENST00000587525 CACNA1A-013 protein_coding Homo_sapiens 0 2279
ENST00000590205 CACNA1A-009 retained_intron Homo_sapiens 0 327
ENST00000593160 CACNA1A-014 retained_intron Homo_sapiens 0 634
ENST00000593267 CACNA1A-010 retained_intron Homo_sapiens 0 429
ENST00000614285 CACNA1A-201 protein_coding Homo_sapiens 0 4536

Loading