C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000399959 DDX3X-001 ENSG00000215301 9606 + X:41333398-41350274 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; MuscleOvaryPlacentaTestisENST00000399959
Transcript ID Muscle Ovary Placenta Testis
ENST00000399959 4.177±0.00 33.464±12.00 31.434±0.00 18.865±2.51

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005QB CIL_0005QB_0001 CGP X:41085635-41364472
CIL_0007LW CIL_0007LW_0001 UCNEbase X:41232520-41520330
CIL_0001X4 CIL_0001X4_0002 CGP X:41333348-41475710

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003676 IEA nucleic acid binding
GO:0003677 IDA DNA binding
GO:0003723 IDA RNA binding
GO:0004003 IDA ATP-dependent DNA helicase activity
GO:0004004 IDA ATP-dependent RNA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005741 IEA mitochondrial outer membrane
GO:0005852 IDA eukaryotic translation initiation factor 3 complex
GO:0006200 IEA ATP catabolic process
GO:0006351 IEA transcription, DNA-templated
GO:0007059 IMP chromosome segregation
GO:0008134 IDA transcription factor binding
GO:0008143 IDA poly(A) binding
GO:0008190 IDA eukaryotic initiation factor 4E binding
GO:0008625 IMP extrinsic apoptotic signaling pathway via death domain receptors
GO:0009615 IDA response to virus
GO:0010494 IDA cytoplasmic stress granule
GO:0010501 IDA RNA secondary structure unwinding
GO:0016032 IEA viral process
GO:0016887 IDA ATPase activity
GO:0017148 IMP negative regulation of translation
GO:0022627 IDA cytosolic small ribosomal subunit
GO:0030307 IMP positive regulation of cell growth
GO:0030308 IDA negative regulation of cell growth
GO:0031333 IDA negative regulation of protein complex assembly
GO:0031369 IDA translation initiation factor binding
GO:0032508 IDA DNA duplex unwinding
GO:0032728 TAS positive regulation of interferon-beta production
GO:0034063 IDA stress granule assembly
GO:0035556 IDA intracellular signal transduction
GO:0035613 IDA RNA stem-loop binding
GO:0042256 IMP mature ribosome assembly
GO:0043024 IDA ribosomal small subunit binding
GO:0043065 IMP positive regulation of apoptotic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0043154 IMP negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043280 IMP positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044822 IDA poly(A) RNA binding
GO:0045087 IMP innate immune response
GO:0045727 IDA positive regulation of translation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0045948 IMP positive regulation of translational initiation
GO:0048027 IDA mRNA 5'-UTR binding
GO:0070062 IDA extracellular vesicular exosome
GO:0071243 IDA cellular response to arsenic-containing substance
GO:0071470 IDA cellular response to osmotic stress
GO:0071651 TAS positive regulation of chemokine (C-C motif) ligand 5 production
GO:0097193 IMP intrinsic apoptotic signaling pathway
GO:1900087 IMP positive regulation of G1/S transition of mitotic cell cycle
GO:2001243 IMP negative regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000000804 Ddx3x-001 protein_coding Mus_musculus 0 6972
ENSMUST00000045108 D1Pas1-001 protein_coding Mus_musculus 0 2695
ENSMUST00000091190 Ddx3y-001 protein_coding Mus_musculus 0 2230
ENSMUST00000188484 Ddx3y-002 nonsense_mediated_decay Mus_musculus 0 2148
ENSMUST00000189614 RP23-12H12.1-001 processed_pseudogene Mus_musculus 0 920
ENSMUST00000149639 Ddx3x-005 retained_intron Mus_musculus 0 904
ENSMUST00000153611 Ddx3x-003 retained_intron Mus_musculus 0 737
ENSMUST00000123096 Ddx3x-004 retained_intron Mus_musculus 0 643
ENSMUST00000188182 Ddx3y-003 retained_intron Mus_musculus 0 640
ENSMUST00000153851 Ddx3x-002 processed_transcript Mus_musculus 0 505
ENSDART00000006867 ddx3-001 protein_coding Danio_rerio 0 353
ENSDART00000102148 pl10-001 protein_coding Danio_rerio 0 241

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