C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polypyrimidine tract binding protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000006498 Ptbp1 10090 + 10:79854427-79864771 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000057343 Ptbp1-008 79854652-79863424 nonsense_mediated_decay
  ENSMUST00000095457 Ptbp1-005 79854668-79864359 protein_coding
  ENSMUST00000099958 Ptbp1-009 79854641-79859613 processed_transcript
  ENSMUST00000164385 Ptbp1-018 79861738-79863050 retained_intron
  ENSMUST00000165153 Ptbp1-004 79854633-79863818 retained_intron
  ENSMUST00000165704 Ptbp1-002 79854629-79864771 protein_coding
  ENSMUST00000165724 Ptbp1-017 79859650-79863053 nonsense_mediated_decay
  ENSMUST00000168216 Ptbp1-011 79854667-79859044 processed_transcript
  ENSMUST00000168683 Ptbp1-014 79855038-79859096 protein_coding
  ENSMUST00000168988 Ptbp1-013 79854605-79859712 retained_intron
  ENSMUST00000169091 Ptbp1-015 79858772-79859387 protein_coding
  ENSMUST00000169483 Ptbp1-012 79854667-79859364 nonsense_mediated_decay
  ENSMUST00000169580 Ptbp1-006 79862017-79864432 retained_intron
  ENSMUST00000171216 Ptbp1-016 79858994-79860125 retained_intron
  ENSMUST00000171599 Ptbp1-010 79854665-79859014 protein_coding
  ENSMUST00000172282 Ptbp1-001 79854427-79864432 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000057343ENSMUST00000095457ENSMUST00000165153ENSMUST00000165704ENSMUST00000165724ENSMUST00000169580ENSMUST00000171216ENSMUST00000172282
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000057343 N/A N/A 21.296±0.28 N/A N/A N/A N/A 41.087±8.69 N/A N/A N/A 23.764±9.91 N/A
ENSMUST00000095457 21.636±0.00 20.585±4.54 12.957±1.04 21.177±8.12 25.892±10.40 4.854±1.35 20.345±6.41 26.479±15.02 20.001±0.55 1.708±0.25 36.874±8.95 41.258±29.86 6.653±1.98
ENSMUST00000165153 N/A 15.748±0.91 19.134±0.00 N/A 23.512±5.67 N/A N/A 23.110±16.73 N/A 1.486±0.00 38.047±5.13 61.018±26.19 N/A
ENSMUST00000165704 27.173±5.73 21.068±4.37 N/A 14.440±0.64 20.334±2.35 3.934±0.00 20.014±4.68 7.806±0.53 26.672±5.50 N/A 45.166±7.70 N/A 10.284±0.00
ENSMUST00000165724 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 100.600±0.00 60.461±30.23 12.852±0.00
ENSMUST00000169580 N/A N/A N/A 9.383±0.00 N/A 3.331±0.00 N/A N/A N/A 1.722±0.41 34.020±3.90 N/A N/A
ENSMUST00000171216 110.145±0.08 N/A N/A 20.252±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000172282 32.507±4.87 37.468±10.61 18.876±2.24 21.429±8.52 23.584±3.90 5.143±1.40 24.652±1.95 24.920±12.45 25.099±3.29 2.187±0.73 40.644±13.89 39.517±2.28 19.947±0.85

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XG CIL_0008XG_0002 VISTA 10:79539861-80142369
CIL_00051Q CIL_00051Q_0002 CGP 10:79821021-79864771
CIL_00008B CIL_00008B_0002 CGP 10:79854427-79874634

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000381 IEA regulation of alternative mRNA splicing, via spliceosome
GO:0003723 IEA RNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006397 IEA mRNA processing
GO:0016020 IEA membrane
GO:0033119 IEA negative regulation of RNA splicing
GO:0036002 IEA pre-mRNA binding
GO:0044822 IEA poly(A) RNA binding
GO:0048025 IMP negative regulation of mRNA splicing, via spliceosome
GO:0051148 IEA negative regulation of muscle cell differentiation
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019362 ptbp1a polypyrimidine tract binding protein 1a protein_coding Danio_rerio
ENSDARG00000031907 ptbp1b polypyrimidine tract binding protein 1b protein_coding Danio_rerio
ENSG00000011304 PTBP1 polypyrimidine tract binding protein 1 protein_coding Homo_sapiens

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