C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, ionotropic, AMPA 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000518783 GRIA1-007 ENSG00000155511 9606 + 5:153492172-153813680 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000518783
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000518783 0.396±0.00 0.037±0.00 4.590±0.00 0.064±0.02 0.142±0.00 0.060±0.00 0.086±0.00 0.058±0.00 0.127±0.00 0.073±0.06 0.021±0.01 0.155±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001UF CIL_0001UF_0001 CGP 5:152391532-153813869
CIL_0001UG CIL_0001UG_0001 CGP 5:153489615-154038936

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004970 IEA ionotropic glutamate receptor activity
GO:0004971 IDA alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:0005234 IBA:IEA extracellular-glutamate-gated ion channel activity
GO:0005515 IPI protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0007165 TAS signal transduction
GO:0007268 TAS synaptic transmission
GO:0007616 IEA long-term memory
GO:0008021 IEA synaptic vesicle
GO:0008066 TAS glutamate receptor activity
GO:0008328 IEA ionotropic glutamate receptor complex
GO:0009986 ISS cell surface
GO:0014069 ISS postsynaptic density
GO:0016020 IEA membrane
GO:0030054 IEA cell junction
GO:0030165 ISS PDZ domain binding
GO:0030425 ISS dendrite
GO:0030666 TAS endocytic vesicle membrane
GO:0031623 IEA receptor internalization
GO:0032281 ISS alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0032590 IEA dendrite membrane
GO:0034220 IEA ion transmembrane transport
GO:0035235 IEA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0043005 IEA neuron projection
GO:0043025 ISS neuronal cell body
GO:0043197 ISS dendritic spine
GO:0044308 IEA axonal spine
GO:0044309 ISS neuron spine
GO:0045211 IBA postsynaptic membrane
GO:0060292 IEA long term synaptic depression

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000094179 Gria1-005 protein_coding Mus_musculus 0 3725
ENSMUST00000151045 Gria1-006 protein_coding Mus_musculus 0 3531
ENSMUST00000036315 Gria1-004 protein_coding Mus_musculus 0 3531
ENSDART00000074671 gria2b-002 protein_coding Danio_rerio 0 885
ENSDART00000102782 gria2a-001 protein_coding Danio_rerio 0 837
ENSMUST00000165288 Gria3-201 protein_coding Mus_musculus 0 797
ENSMUST00000115103 Gria3-004 protein_coding Mus_musculus 0 797
ENSMUST00000027020 Gria4-201 protein_coding Mus_musculus 0 793
ENSMUST00000075316 Gria2-201 protein_coding Mus_musculus 0 773
ENSDART00000043180 gria3b-001 protein_coding Danio_rerio 0 745
ENSDART00000044735 gria1b-001 protein_coding Danio_rerio 0 734
ENSDART00000021437 gria1a-001 protein_coding Danio_rerio 0 713
ENSMUST00000139965 Gria3-002 nonsense_mediated_decay Mus_musculus 0 699
ENSMUST00000173531 Gria1-007 processed_transcript Mus_musculus 0 505
ENSMUST00000156721 Gria3-003 retained_intron Mus_musculus 0 248
ENSMUST00000125292 Gria1-003 protein_coding Mus_musculus 0 191

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