C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: paired box 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000419022 PAX6-201 ENSG00000007372 9606 - 11:31784792-31817961 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainKidneyOvaryENST00000419022
Transcript ID Brain Kidney Ovary
ENST00000419022 0.465±0.00 0.018±0.00 0.033±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008KI CIL_0008KI_0001 VISTA 11:31301275-31902571
CIL_0007UQ CIL_0007UQ_0001 VISTA 11:31363809-31965336
CIL_0008UP CIL_0008UP_0001 VISTA 11:31463875-32065678
CIL_0007XG CIL_0007XG_0001 VISTA 11:31494904-32096873
CIL_000914 CIL_000914_0001 VISTA 11:31574048-32177516
CIL_0007JA CIL_0007JA_0002 UCNEbase 11:31639896-31819124
CIL_0007PY CIL_0007PY_0001 VISTA 11:31667627-32268476
CIL_00096J CIL_00096J_0001 VISTA 11:31730852-32331950

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000132 IEA establishment of mitotic spindle orientation
GO:0000790 IDA nuclear chromatin
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001227 IEA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001228 IEA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001568 IMP blood vessel development
GO:0001654 TAS eye development
GO:0001709 IEA cell fate determination
GO:0001755 IEA neural crest cell migration
GO:0001764 IEA neuron migration
GO:0001933 IEA negative regulation of protein phosphorylation
GO:0002052 IEA positive regulation of neuroblast proliferation
GO:0002064 IEA epithelial cell development
GO:0002088 IEA lens development in camera-type eye
GO:0003309 IEA type B pancreatic cell differentiation
GO:0003310 IEA pancreatic A cell differentiation
GO:0003322 IMP pancreatic A cell development
GO:0003677 TAS:IEA DNA binding
GO:0003680 IEA AT DNA binding
GO:0003682 IEA chromatin binding
GO:0003690 IEA double-stranded DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0004842 ISS ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006366 IMP transcription from RNA polymerase II promoter
GO:0007224 IEA smoothened signaling pathway
GO:0007409 IEA axonogenesis
GO:0007411 IEA axon guidance
GO:0007417 TAS central nervous system development
GO:0007420 IEA brain development
GO:0007435 IEA salivary gland morphogenesis
GO:0007601 TAS visual perception
GO:0008134 ISS transcription factor binding
GO:0008285 IEA negative regulation of cell proliferation
GO:0009611 IEP response to wounding
GO:0009786 IEA regulation of asymmetric cell division
GO:0009887 TAS organ morphogenesis
GO:0009950 IEA dorsal/ventral axis specification
GO:0009952 IEA anterior/posterior pattern specification
GO:0009953 IEA dorsal/ventral pattern formation
GO:0010468 IEA regulation of gene expression
GO:0010628 IMP positive regulation of gene expression
GO:0010975 IEA regulation of neuron projection development
GO:0016567 ISS protein ubiquitination
GO:0019901 ISS protein kinase binding
GO:0021510 IEA spinal cord development
GO:0021543 IEA pallium development
GO:0021549 IEA cerebellum development
GO:0021593 IEA rhombomere morphogenesis
GO:0021772 IEA olfactory bulb development
GO:0021778 IEA oligodendrocyte cell fate specification
GO:0021796 IEA cerebral cortex regionalization
GO:0021797 IEA forebrain anterior/posterior pattern specification
GO:0021798 IEA forebrain dorsal/ventral pattern formation
GO:0021902 IEA commitment of neuronal cell to specific neuron type in forebrain
GO:0021905 IEA forebrain-midbrain boundary formation
GO:0021912 IEA regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification
GO:0021913 IEA regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification
GO:0021918 IEA regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment
GO:0021978 IEA telencephalon regionalization
GO:0021983 IEA pituitary gland development
GO:0022027 IEA interkinetic nuclear migration
GO:0023019 IEA signal transduction involved in regulation of gene expression
GO:0030154 IEA cell differentiation
GO:0030216 IEA keratinocyte differentiation
GO:0030334 IEA regulation of cell migration
GO:0030858 IEA positive regulation of epithelial cell differentiation
GO:0030900 IEA forebrain development
GO:0030902 IEA hindbrain development
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032808 IEA lacrimal gland development
GO:0032869 IEA cellular response to insulin stimulus
GO:0033365 IEA protein localization to organelle
GO:0035035 ISS histone acetyltransferase binding
GO:0035690 IEA cellular response to drug
GO:0042462 IEA eye photoreceptor cell development
GO:0042593 IMP glucose homeostasis
GO:0042660 IEA positive regulation of cell fate specification
GO:0043010 IEA camera-type eye development
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0044344 IEA cellular response to fibroblast growth factor stimulus
GO:0045165 IEA cell fate commitment
GO:0045471 IEA response to ethanol
GO:0045664 IEA regulation of neuron differentiation
GO:0045665 IEA negative regulation of neuron differentiation
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0048505 IEA regulation of timing of cell differentiation
GO:0048596 IEA embryonic camera-type eye morphogenesis
GO:0048663 NAS neuron fate commitment
GO:0048708 IEA astrocyte differentiation
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:0050767 IEA regulation of neurogenesis
GO:0050768 ISS negative regulation of neurogenesis
GO:0060041 IEA retina development in camera-type eye
GO:0061072 IMP iris morphogenesis
GO:0061303 IMP cornea development in camera-type eye
GO:0061351 IEA neural precursor cell proliferation
GO:0070094 IEA positive regulation of glucagon secretion
GO:0070410 IEA co-SMAD binding
GO:0070412 IPI R-SMAD binding
GO:0071333 IEA cellular response to glucose stimulus
GO:0071380 IEA cellular response to prostaglandin E stimulus
GO:0071837 IEA HMG box domain binding
GO:1901142 IEA insulin metabolic process
GO:2000178 IEA negative regulation of neural precursor cell proliferation
GO:2001224 IEA positive regulation of neuron migration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000167211 Pax6-201 protein_coding Mus_musculus 0 3282
ENSMUST00000111085 Pax6-008 protein_coding Mus_musculus 0 3260
ENSMUST00000111086 Pax6-001 protein_coding Mus_musculus 0 3254
ENSMUST00000111087 Pax6-002 protein_coding Mus_musculus 0 2854
ENSMUST00000111082 Pax6-012 protein_coding Mus_musculus 0 2848
ENSMUST00000090391 Pax6-013 protein_coding Mus_musculus 0 2843
ENSMUST00000090397 Pax6-011 protein_coding Mus_musculus 0 2693
ENSMUST00000146803 Pax6-026 processed_transcript Mus_musculus 0 2527
ENSMUST00000111083 Pax6-009 protein_coding Mus_musculus 0 2444
ENSMUST00000154643 Pax6-014 retained_intron Mus_musculus 0 1365
ENSMUST00000140173 Pax6-019 processed_transcript Mus_musculus 0 1210
ENSMUST00000123063 Pax6-003 processed_transcript Mus_musculus 0 1116
ENSMUST00000111088 Pax6-004 protein_coding Mus_musculus 0 1107
ENSDART00000128877 pax6a-203 protein_coding Danio_rerio 0 1033
ENSDART00000148420 pax6a-001 protein_coding Danio_rerio 0 1033
ENSDART00000129319 pax6a-204 protein_coding Danio_rerio 0 1020
ENSDART00000131523 pax6a-005 protein_coding Danio_rerio 0 1020
ENSMUST00000135412 Pax6-020 processed_transcript Mus_musculus 0 972
ENSMUST00000153011 Pax6-018 processed_transcript Mus_musculus 0 898
ENSDART00000066224 pax6a-201 protein_coding Danio_rerio 0 861
ENSDART00000124577 pax6a-202 protein_coding Danio_rerio 0 861
ENSDART00000066225 pax6a-002 protein_coding Danio_rerio 0 861
ENSDART00000145946 pax6b-001 protein_coding Danio_rerio 0 826
ENSMUST00000155081 Pax6-023 processed_transcript Mus_musculus 0 808
ENSMUST00000156216 Pax6-017 protein_coding Mus_musculus 0 760
ENSDART00000133390 pax6a-009 protein_coding Danio_rerio 0 660
ENSMUST00000138365 Pax6-021 processed_transcript Mus_musculus 0 628
ENSMUST00000145744 Pax6-022 processed_transcript Mus_musculus 0 604
ENSDART00000132425 pax6a-006 protein_coding Danio_rerio 0 580
ENSDART00000139544 pax6a-008 protein_coding Danio_rerio 0 503
ENSDART00000014572 pax6b-201 protein_coding Danio_rerio 0 459
ENSMUST00000122965 Elp4-001 protein_coding Mus_musculus 0 449
ENSMUST00000147946 Pax6-027 retained_intron Mus_musculus 0 348
ENSMUST00000142772 Pax6-015 protein_coding Mus_musculus 0 281
ENSMUST00000123000 Pax6-025 retained_intron Mus_musculus 0 231
ENSMUST00000154302 Pax6-024 retained_intron Mus_musculus 0 231
ENSMUST00000172990 Pax6-010 processed_transcript Mus_musculus 1.99965e-42 180
ENSMUST00000147923 Pax6-005 processed_transcript Mus_musculus 6.99949e-42 178
ENSMUST00000153639 Pax6-016 retained_intron Mus_musculus 3e-25 122

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