C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: actinin alpha 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000064204 Actn2-001 ENSMUSG00000052374 10090 - 13:12269426-12340760 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000064204
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000064204 0.074±0.02 0.037±0.02 0.370±0.01 1.736±1.29 9.833±9.64 0.653±0.30 175.253±34.93 1.198±1.13 0.573±1.04 6.668±3.17 117.405±26.09 0.342±0.11 0.056±0.03 0.469±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008J8 CIL_0008J8_0002 VISTA 13:11813964-12415326
CIL_0008J9 CIL_0008J9_0002 VISTA 13:11824772-12428580
CIL_0008IY CIL_0008IY_0002 VISTA 13:11831518-12433920
CIL_00097Y CIL_00097Y_0002 VISTA 13:12065828-12670427

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005865 TAS striated muscle thin filament
GO:0005925 IEA focal adhesion
GO:0006936 IDA muscle contraction
GO:0008092 IDA cytoskeletal protein binding
GO:0030017 IDA sarcomere
GO:0030018 IDA Z disc
GO:0030035 IEA microspike assembly
GO:0030175 IEA filopodium
GO:0030274 IPI LIM domain binding
GO:0030374 IDA ligand-dependent nuclear receptor transcription coactivator activity
GO:0030375 IDA thyroid hormone receptor coactivator activity
GO:0030674 TAS protein binding, bridging
GO:0030864 IEA cortical actin cytoskeleton
GO:0031432 IEA titin binding
GO:0042391 IEA regulation of membrane potential
GO:0042802 IEA identical protein binding
GO:0042803 TAS protein homodimerization activity
GO:0043267 IEA negative regulation of potassium ion transport
GO:0043268 IEA positive regulation of potassium ion transport
GO:0044325 IEA ion channel binding
GO:0046983 IEA protein dimerization activity
GO:0048041 IEA focal adhesion assembly
GO:0051015 IDA actin filament binding
GO:0051289 IEA protein homotetramerization
GO:0051373 IEA FATZ binding
GO:0070062 IEA extracellular vesicular exosome
GO:0070080 IEA titin Z domain binding
GO:1901017 IEA negative regulation of potassium ion transmembrane transporter activity
GO:1901018 IEA positive regulation of potassium ion transmembrane transporter activity
GO:2000009 IEA negative regulation of protein localization to cell surface
GO:2000273 IDA positive regulation of receptor activity
GO:2001141 IDA regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000005682 actn3a-001 protein_coding Danio_rerio 0 1611
ENSDART00000032887 ACTN4 (1 of 3)-201 protein_coding Danio_rerio 0 547
ENST00000193403 ACTN1-001 protein_coding Homo_sapiens 0 1740
ENST00000252699 ACTN4-001 protein_coding Homo_sapiens 0 1531
ENST00000366578 ACTN2-001 protein_coding Homo_sapiens 0 3694
ENST00000376839 ACTN1-007 protein_coding Homo_sapiens 0 1759
ENST00000390009 ACTN4-010 protein_coding Homo_sapiens 0 1096
ENST00000394419 ACTN1-005 protein_coding Homo_sapiens 0 1674
ENST00000438964 ACTN1-002 protein_coding Homo_sapiens 0 1842
ENST00000461367 ACTN2-002 processed_transcript Homo_sapiens 0 1116
ENST00000492634 ACTN2-004 processed_transcript Homo_sapiens 0 1037
ENST00000494762 ACTN2-003 processed_transcript Homo_sapiens 0 544
ENST00000502692 ACTN3-003 protein_coding Homo_sapiens 0 1493
ENST00000511191 ACTN3-005 nonsense_mediated_decay Homo_sapiens 0 324
ENST00000513398 ACTN3-001 protein_coding Homo_sapiens 0 1578
ENST00000538545 ACTN1-006 protein_coding Homo_sapiens 0 1796
ENST00000542672 ACTN2-201 protein_coding Homo_sapiens 0 3650
ENST00000544964 ACTN1-019 protein_coding Homo_sapiens 0 296
ENST00000546208 ACTN2-202 protein_coding Homo_sapiens 0 2619
ENST00000553290 ACTN1-020 protein_coding Homo_sapiens 0 388
ENST00000555075 ACTN1-022 protein_coding Homo_sapiens 0 390
ENST00000556083 ACTN1-008 retained_intron Homo_sapiens 0 763
ENST00000556432 ACTN1-023 retained_intron Homo_sapiens 0 326
ENST00000586538 ACTN4-012 protein_coding Homo_sapiens 0 394
ENST00000588618 ACTN4-007 retained_intron Homo_sapiens 0 965

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