C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sodium channel, voltage gated, type VIII, alpha subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000354534 SCN8A-001 ENSG00000196876 9606 + 12:51591236-51812864 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainENST00000354534
Transcript ID Brain
ENST00000354534 5.685±3.39

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006JW CIL_0006JW_0001 CGP 12:51391317-51812864

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001518 IC:IEA voltage-gated sodium channel complex
GO:0005216 IEA ion channel activity
GO:0005248 IDA:IEA voltage-gated sodium channel activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005886 IBA plasma membrane
GO:0006811 IEA ion transport
GO:0006814 NAS:IEA sodium ion transport
GO:0007399 TAS nervous system development
GO:0007411 TAS axon guidance
GO:0007422 ISS peripheral nervous system development
GO:0007517 IEA muscle organ development
GO:0007605 IEA sensory perception of sound
GO:0007626 IEA locomotory behavior
GO:0007628 IEA adult walking behavior
GO:0008344 IEA adult locomotory behavior
GO:0009636 IEA response to toxic substance
GO:0016020 IEA membrane
GO:0016021 TAS integral component of membrane
GO:0019228 IBA neuronal action potential
GO:0030018 ISS Z disc
GO:0030425 IEA dendrite
GO:0031410 IEA cytoplasmic vesicle
GO:0033268 ISS node of Ranvier
GO:0034706 IEA sodium channel complex
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0042552 ISS myelination
GO:0043025 IEA neuronal cell body
GO:0043194 ISS axon initial segment
GO:0050905 IEA neuromuscular process
GO:0055085 IEA transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000082209 Scn8a-201 protein_coding Mus_musculus 0 8165
ENSMUST00000108910 Scn8a-205 protein_coding Mus_musculus 0 8059
ENSMUST00000108908 Scn8a-203 protein_coding Mus_musculus 0 5498
ENSMUST00000108909 Scn8a-204 protein_coding Mus_musculus 0 4403
ENSDART00000022761 scn8ab-201 protein_coding Danio_rerio 0 2405
ENSDART00000151299 scn8ab-001 protein_coding Danio_rerio 0 2405
ENSMUST00000112371 Scn1a-201 protein_coding Mus_musculus 0 1483
ENSMUST00000094951 Scn1a-005 protein_coding Mus_musculus 0 1483
ENSMUST00000077489 Scn1a-004 protein_coding Mus_musculus 0 1483
ENSMUST00000112366 Scn1a-001 protein_coding Mus_musculus 0 1483
ENSMUST00000021056 Scn4a-001 protein_coding Mus_musculus 0 1201
ENSMUST00000065196 Scn5a-201 protein_coding Mus_musculus 0 976
ENSMUST00000120420 Scn5a-002 protein_coding Mus_musculus 0 976
ENSMUST00000117911 Scn5a-001 protein_coding Mus_musculus 0 976
ENSDART00000044157 scn4ab-001 protein_coding Danio_rerio 0 830
ENSDART00000104004 scn4ab-201 protein_coding Danio_rerio 0 828
ENSMUST00000156865 Scn1a-003 processed_transcript Mus_musculus 0 745
ENSDART00000097722 SCN11A-201 protein_coding Danio_rerio 0 608
ENSMUST00000096198 Scn8a-202 protein_coding Mus_musculus 0 483
ENSMUST00000100067 Scn2a1-201 protein_coding Mus_musculus 0 472
ENSMUST00000028377 Scn2a1-001 protein_coding Mus_musculus 0 472
ENSMUST00000066432 Scn3a-201 protein_coding Mus_musculus 0 444
ENSMUST00000100069 Scn3a-001 protein_coding Mus_musculus 0 438
ENSMUST00000100063 Scn9a-201 protein_coding Mus_musculus 0 383
ENSMUST00000164384 Scn9a-202 protein_coding Mus_musculus 0 383
ENSMUST00000112354 Scn9a-002 protein_coding Mus_musculus 0 383
ENSMUST00000100064 Scn9a-001 protein_coding Mus_musculus 0 383
ENSMUST00000138368 Scn2a1-003 processed_transcript Mus_musculus 3e-23 117
ENSMUST00000006311 Tead4-001 protein_coding Mus_musculus 0.000005 60

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