C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: actin, alpha, cardiac muscle 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000290378 ACTC1-001 ENSG00000159251 9606 - 15:34788096-34796139 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000290378
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000290378 0.512±0.00 1.828±0.00 0.029±0.00 0.145±0.00 0.222±0.07 0.223±0.20 487.553±367.86 1.463±0.00 8.394±8.29 1.834±0.26 16.303±11.93 0.223±0.12 1.676±1.12 6.058±5.92

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008VH CIL_0008VH_0001 VISTA 15:34591431-35191947
CIL_0005II CIL_0005II_0002 CGP 15:34751032-34796139
CIL_0006HF CIL_0006HF_0001 CGP 15:34788096-34969839

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005524 IDA ATP binding
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005884 IDA actin filament
GO:0005925 IDA focal adhesion
GO:0006200 IDA ATP catabolic process
GO:0006915 ISS apoptotic process
GO:0016020 IDA membrane
GO:0016887 IDA ATPase activity
GO:0017022 IPI myosin binding
GO:0030017 IDA sarcomere
GO:0030048 IDA actin filament-based movement
GO:0030049 TAS muscle filament sliding
GO:0030240 ISS skeletal muscle thin filament assembly
GO:0031032 ISS actomyosin structure organization
GO:0031674 ISS I band
GO:0033275 IMP actin-myosin filament sliding
GO:0042493 IEA response to drug
GO:0042643 IDA actomyosin, actin portion
GO:0043066 IEA negative regulation of apoptotic process
GO:0045471 IEA response to ethanol
GO:0055003 ISS cardiac myofibril assembly
GO:0055008 ISS cardiac muscle tissue morphogenesis
GO:0060047 IMP heart contraction
GO:0060048 IEA cardiac muscle contraction
GO:0070062 IDA extracellular vesicular exosome
GO:0070252 IEA actin-mediated cell contraction
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000090269 Actc1-001 protein_coding Mus_musculus 0 1886
ENSDART00000058629 acta1b-001 protein_coding Danio_rerio 0 1327
ENSMUST00000034453 Acta1-201 protein_coding Mus_musculus 0 1323
ENSDART00000055136 actc1b-201 protein_coding Danio_rerio 0 1291
ENSDART00000052838 acta1a-001 protein_coding Danio_rerio 0 1266
ENSMUST00000121731 Actg2-002 protein_coding Mus_musculus 0 1194
ENSMUST00000075161 Actg2-001 protein_coding Mus_musculus 0 1194
ENSMUST00000100497 Actb-001 protein_coding Mus_musculus 0 1162
ENSMUST00000106215 Actg1-201 protein_coding Mus_musculus 0 1064
ENSMUST00000071555 Actg1-001 protein_coding Mus_musculus 0 1064
ENSMUST00000121430 Gm12715-001 processed_pseudogene Mus_musculus 0 1062
ENSDART00000109883 ACTC1 (2 of 2)-002 protein_coding Danio_rerio 0 1042
ENSMUST00000082300 Gm8399-201 pseudogene Mus_musculus 0 1014
ENSMUST00000078717 Lrrc58-001 protein_coding Mus_musculus 0 917
ENSMUST00000119947 Gm15725-001 transcribed_processed_pseudogene Mus_musculus 0 911
ENSMUST00000141904 Actg2-005 protein_coding Mus_musculus 0 822
ENSMUST00000120059 Gm5388-001 processed_pseudogene Mus_musculus 0 813
ENSMUST00000171419 Actb-007 protein_coding Mus_musculus 0 809
ENSMUST00000167721 Actb-002 protein_coding Mus_musculus 0 785
ENSMUST00000146697 Gm8464-001 transcribed_processed_pseudogene Mus_musculus 0 771
ENSMUST00000140208 Gm8464-002 processed_transcript Mus_musculus 0 771
ENSMUST00000151942 Gm4750-001 transcribed_processed_pseudogene Mus_musculus 0 771
ENSMUST00000152262 Gm4750-002 processed_transcript Mus_musculus 0 771
ENSMUST00000119663 Gm4760-001 processed_pseudogene Mus_musculus 0 619
ENSMUST00000152029 Actg2-004 protein_coding Mus_musculus 0 588
ENSMUST00000128055 Actg1-005 protein_coding Mus_musculus 0 582
ENSMUST00000119420 Gm4918-001 processed_pseudogene Mus_musculus 0 508
ENSMUST00000106216 Actb-006 protein_coding Mus_musculus 0 477
ENSMUST00000165629 Actb-008 retained_intron Mus_musculus 0 385
ENSMUST00000167386 Actb-003 processed_transcript Mus_musculus 0 383
ENSMUST00000165006 Gm17228-001 processed_pseudogene Mus_musculus 0 379
ENSMUST00000156343 Actg1-004 retained_intron Mus_musculus 0 326
ENSMUST00000141406 Actg1-007 retained_intron Mus_musculus 0 322
ENSMUST00000131103 Actg1-002 nonsense_mediated_decay Mus_musculus 0 322
ENSMUST00000164765 Actb-005 retained_intron Mus_musculus 0 296
ENSDART00000155770 ACTC1 (2 of 2)-001 protein_coding Danio_rerio 0 267
ENSMUST00000124933 Actg2-006 processed_transcript Mus_musculus 0 209
ENSMUST00000144868 Actg1-003 retained_intron Mus_musculus 1.4013e-45 189
ENSMUST00000118358 Gm14610-001 processed_pseudogene Mus_musculus 0.0000000000003 82

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