C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: platelet derived growth factor receptor, alpha polypeptide
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000168162 Pdgfra-202 ENSMUSG00000029231 10090 + 5:75156166-75198204 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000168162
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000168162 3.264±1.67 1.107±0.32 2.990±0.59 0.944±0.58 2.262±0.44 1.537±0.00 1.140±0.09 1.224±0.18 0.207±0.06 4.670±0.01 0.947±0.37 7.621±3.37 11.372±7.74 0.402±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007R1 CIL_0007R1_0002 VISTA 5:74712461-75313668
CIL_0008IT CIL_0008IT_0002 VISTA 5:74771388-75372201
CIL_0001CO CIL_0001CO_0002 CGP 5:75075464-75198204
CIL_0001CJ CIL_0001CJ_0002 CGP 5:75152291-75656722

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001553 IGI luteinization
GO:0001701 IMP in utero embryonic development
GO:0002244 IMP hematopoietic progenitor cell differentiation
GO:0005018 ISS platelet-derived growth factor alpha-receptor activity
GO:0005021 ISS vascular endothelial growth factor-activated receptor activity
GO:0005161 IEA platelet-derived growth factor receptor binding
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005887 ISS integral component of plasma membrane
GO:0005902 IDA microvillus
GO:0007204 ISS positive regulation of cytosolic calcium ion concentration
GO:0008210 IGI estrogen metabolic process
GO:0008284 ISS positive regulation of cell proliferation
GO:0008585 IGI female gonad development
GO:0009653 IMP anatomical structure morphogenesis
GO:0009887 IMP organ morphogenesis
GO:0009897 IDA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0010544 ISS negative regulation of platelet activation
GO:0010863 IEA positive regulation of phospholipase C activity
GO:0016020 IEA membrane
GO:0016477 IMP cell migration
GO:0018108 ISS peptidyl-tyrosine phosphorylation
GO:0023019 IDA signal transduction involved in regulation of gene expression
GO:0030198 IMP extracellular matrix organization
GO:0030324 IMP lung development
GO:0030325 IGI adrenal gland development
GO:0030335 ISS positive regulation of cell migration
GO:0030539 IMP male genitalia development
GO:0031226 IEA intrinsic component of plasma membrane
GO:0033327 IMP Leydig cell differentiation
GO:0035790 IDA platelet-derived growth factor receptor-alpha signaling pathway
GO:0038085 IEA vascular endothelial growth factor binding
GO:0038091 ISS positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway
GO:0042060 IMP wound healing
GO:0042475 IMP odontogenesis of dentin-containing tooth
GO:0042803 ISS protein homodimerization activity
GO:0043552 ISS positive regulation of phosphatidylinositol 3-kinase activity
GO:0045740 ISS positive regulation of DNA replication
GO:0046777 ISS protein autophosphorylation
GO:0048008 IMP platelet-derived growth factor receptor signaling pathway
GO:0048015 ISS phosphatidylinositol-mediated signaling
GO:0048146 ISS positive regulation of fibroblast proliferation
GO:0048407 IDA platelet-derived growth factor binding
GO:0048557 IMP embryonic digestive tract morphogenesis
GO:0048701 IMP embryonic cranial skeleton morphogenesis
GO:0048705 IMP skeletal system morphogenesis
GO:0050920 IEA regulation of chemotaxis
GO:0055003 IGI cardiac myofibril assembly
GO:0060021 IMP palate development
GO:0060325 IMP face morphogenesis
GO:0060326 IMP cell chemotaxis
GO:0061298 IGI retina vasculature development in camera-type eye
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade
GO:0070527 ISS platelet aggregation
GO:0071230 IDA cellular response to amino acid stimulus
GO:0072277 IGI metanephric glomerular capillary formation
GO:2000739 ISS regulation of mesenchymal stem cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000028255 pdgfrb-201 protein_coding Danio_rerio 8.99998e-41 174
ENST00000244763 SSR1-001 protein_coding Homo_sapiens 0.00005 57
ENST00000254691 CARD6-001 protein_coding Homo_sapiens 0.000006 58
ENST00000257290 PDGFRA-001 protein_coding Homo_sapiens 0 4124
ENST00000261292 LIPG-001 protein_coding Homo_sapiens 0.000004 60
ENST00000261842 AP4E1-001 protein_coding Homo_sapiens 0.00003 57
ENST00000274276 OSMR-001 protein_coding Homo_sapiens 0.00003 57
ENST00000286719 PPEF2-001 protein_coding Homo_sapiens 0.00002 57
ENST00000304734 RPL7L1-001 protein_coding Homo_sapiens 0.00007 55
ENST00000311765 PDP2-001 protein_coding Homo_sapiens 0.00004 57
ENST00000321844 RP11-111M22.2-201 protein_coding Homo_sapiens 0.000002 60
ENST00000325881 SNX22-001 protein_coding Homo_sapiens 0.000005 58
ENST00000330501 ZNF397-001 protein_coding Homo_sapiens 0.0003 53
ENST00000340855 IDS-001 protein_coding Homo_sapiens 0.0001 55
ENST00000358293 FAM217B-003 protein_coding Homo_sapiens 0.00009 55
ENST00000359047 TRPM6-002 protein_coding Homo_sapiens 0.00003 55
ENST00000359680 TRAPPC2-201 protein_coding Homo_sapiens 0.00001 57
ENST00000360816 FAM217B-002 protein_coding Homo_sapiens 0.00009 55
ENST00000370205 ALG14-001 protein_coding Homo_sapiens 0.00005 57
ENST00000373191 AGO3-003 protein_coding Homo_sapiens 0.0001 57
ENST00000380579 TRAPPC2-002 protein_coding Homo_sapiens 0.00001 57
ENST00000391742 LAIR1-001 protein_coding Homo_sapiens 0.00009 55
ENST00000391898 CARD8-202 protein_coding Homo_sapiens 0.0001 55
ENST00000392238 FAM117B-001 protein_coding Homo_sapiens 0.000002 60
ENST00000394709 HSPA2-001 protein_coding Homo_sapiens 0.0001 55
ENST00000397762 RAB2B-001 protein_coding Homo_sapiens 0.00001 57
ENST00000399702 AC141586.5-002 processed_transcript Homo_sapiens 0.000004 58
ENST00000424702 LSM8-002 protein_coding Homo_sapiens 0.000006 58
ENST00000441564 PSD4-003 protein_coding Homo_sapiens 0.00002 58
ENST00000447740 CARD8-203 protein_coding Homo_sapiens 0.00009 55
ENST00000460436 AIFM1-004 protein_coding Homo_sapiens 0.00003 55
ENST00000461294 PDGFRA-005 retained_intron Homo_sapiens 0 283
ENST00000464497 CLTA-008 nonsense_mediated_decay Homo_sapiens 0.00003 55
ENST00000477853 EMC1-003 protein_coding Homo_sapiens 0.00003 57
ENST00000481349 RP11-568K15.1-005 processed_transcript Homo_sapiens 0.000004 58
ENST00000481865 TNK2-009 retained_intron Homo_sapiens 0.0000006 62
ENST00000488770 MCUR1-002 nonsense_mediated_decay Homo_sapiens 0.00003 55
ENST00000492088 CATSPERG-006 retained_intron Homo_sapiens 0.00002 57
ENST00000492328 ZNF90-004 processed_transcript Homo_sapiens 0.000003 57
ENST00000493763 RPL7L1-003 protein_coding Homo_sapiens 0.00008 55
ENST00000496125 PPP1R37-008 processed_transcript Homo_sapiens 0.000003 57
ENST00000500728 LRPAP1-001 protein_coding Homo_sapiens 0.0001 55
ENST00000501412 RAP1B-012 retained_intron Homo_sapiens 0.000007 57
ENST00000504669 ITGA1-003 retained_intron Homo_sapiens 0.00003 57
ENST00000504771 TNFAIP8-001 protein_coding Homo_sapiens 0.000003 60
ENST00000507166 FIP1L1-005 protein_coding Homo_sapiens 0 1953
ENST00000507536 PDGFRA-004 retained_intron Homo_sapiens 0 667
ENST00000509092 PDGFRA-003 retained_intron Homo_sapiens 0 2012
ENST00000509490 PDGFRA-008 nonsense_mediated_decay Homo_sapiens 0 2182
ENST00000511880 PPEF2-002 nonsense_mediated_decay Homo_sapiens 0.00002 57
ENST00000512375 MRPS18C-002 retained_intron Homo_sapiens 0.00000002 66
ENST00000512931 C4orf22-005 processed_transcript Homo_sapiens 0.000004 57
ENST00000513920 C4orf22-002 nonsense_mediated_decay Homo_sapiens 0.00002 57
ENST00000515210 ERC1-012 processed_transcript Homo_sapiens 0.00001 55
ENST00000518622 CARD8-001 nonsense_mediated_decay Homo_sapiens 0.0001 55
ENST00000519926 LYPLA1-006 processed_transcript Homo_sapiens 0.000004 57
ENST00000534754 SORL1-010 retained_intron Homo_sapiens 0.00004 55
ENST00000545059 ATP6V0A2-004 retained_intron Homo_sapiens 0.000002 60
ENST00000546425 HVCN1-005 retained_intron Homo_sapiens 0.000004 57
ENST00000546428 SLC25A21-002 retained_intron Homo_sapiens 0.0000008 58
ENST00000560390 TM2D3-008 retained_intron Homo_sapiens 0.00006 55
ENST00000560508 AP4E1-002 protein_coding Homo_sapiens 0.00003 57
ENST00000560997 SNX22-006 retained_intron Homo_sapiens 0.000005 58
ENST00000582596 C1orf186-006 processed_transcript Homo_sapiens 0.00002 55
ENST00000591887 ZNF568-010 retained_intron Homo_sapiens 0.00002 57
ENST00000595369 SH2D3A-003 retained_intron Homo_sapiens 0.000001 60
ENST00000602136 MYO1F-012 nonsense_mediated_decay Homo_sapiens 0.00001 55
ENST00000619717 LAIR1-001 protein_coding Homo_sapiens 0.00009 55
ENST00000622513 TTC8-001 protein_coding Homo_sapiens 0.000007 58
ENST00000622984 RP11-111M22.2-001 lincRNA Homo_sapiens 0.000002 60

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